Non-antioxidant activities refer to the biological functions of compounds, classically antioxidant vitamins and phytochemicals, that arise through mechanisms other than direct free-radical scavenging. Ascorbate (vitamin C) is the paradigmatic example: beyond reducing reactive oxygen species, it acts as an essential …
Non-antioxidant activities refer to the biological functions of compounds, classically antioxidant vitamins and phytochemicals, that arise through mechanisms other than direct free-radical scavenging. Ascorbate (vitamin C) is the paradigmatic example: beyond reducing reactive oxygen species, it acts as an essential cofactor for a family of metal-dependent dioxygenases, including prolyl and lysyl hydroxylases required for collagen maturation, enzymes governing carnitine and catecholamine synthesis, and the dioxygenases that regulate transcription factor stability and epigenetic DNA and histone demethylation. Many plant-derived antioxidants likewise exert effects through modulation of enzyme activity, signal transduction, gene expression, and metal homeostasis that are independent of their redox-scavenging capacity, meaning that measured Antioxidant Activity in vitro does not fully predict physiological action. This distinction matters for interpreting how dietary phenolics, flavonoids, and micronutrients influence health. The subject matter in this area includes the antioxidant and phytochemical characterization of medicinal plants and food extracts, comparison of analytical methods for total antioxidant status, evaluation of phenolic and flavonoid constituents, and assessment of antioxidant capacity in supplemented animal models. The journal publishes peer-reviewed research on the broader bioactivities of antioxidant compounds and their non-redox functions.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 103 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Non-antioxidant Activities, linking to each citing work.