Overview
Laboratory animals are non-human species kept and used under controlled conditions for scientific research, testing, and education. Models including rodents such as mice and rats, and other species such as guinea pigs, allow investigators to study physiology, disease mechanisms, and the safety and efficacy of interventions in whole, living systems where human or field study would be impractical or unethical. Their value rests on biological similarity to the processes under study and the ability to control variables, while their use is governed by ethical principles that emphasise replacement, reduction, and refinement and the welfare of the animals. The research gathered here illustrates the experimental roles laboratory animals serve. Toxicology and drug-safety studies use animal models to evaluate the effects and hazards of substances, including investigations of neurotoxicity and oxidative stress in the rodent brain. Inflammation and disease models feature in work using rats to examine systemic inflammatory responses and tissue injury, and guinea pigs in experimental infection and nutrition studies. Other contributions employ animal models to test physiological and dietary interventions and to study organ injury and repair. Together these works reflect the central place of laboratory animals in biomedical and veterinary science as controlled systems through which mechanisms are probed and the effects of treatments are assessed, within an ethical framework for their care and use.
Research published in this journal
9 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Toxicology and Drug Safety Issues: A Review Article
Quercetin Attenuates Manganese-Induced Neurotoxicity in Mice Hippocampus by Regulation of Oxidative Stress and Tumour Necrosis factor Alpha Expression
Antioxidant and Anti-Inflammatory Activities of Biofield Energy Treated Proprietary Test Formulation in Brain Tissues in Cecal Slurry, LPS and E. Coli-Induced Systemic Inflammatory Response Syndrome (SIRS) in Sprague Dawley Rats
Investigation of Emerging Risk Factors and Isolation of Potential Pathogenic Bacteria from Domestic Dog Stool in Port Harcourt Metropolis, Niger Delta
Effect of Graded Levels of Spirulina (Arthropsira platensis) on Feed Intake and in vivo Digestibility of Trypsacum laxum in Guinea Pig (Cavia Porcellus L)
The antioxidant and hepatoprotective activities of two tea polysaccharides
Effect of Bone Marrow and Adipose Mesenchymal Stem Cells on Rat Intestinal Injury Induced by Methotrexate
How this research is being cited
The 9 articles above have been cited 22 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Russian Military Medical Academy Reports
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2025 · International Journal of Biological Macromolecules
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2025 · Food and Chemical Toxicology
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2024 · Journal of Complementary and Integrative Medicine
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2024 · International Journal of Biological Macromolecules
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2024 · Online Journal of Animal and Feed Research
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2024 · Journal of Complementary and Integrative Medicine
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2023 · Journal of Applied Veterinary Science And Technology
A sample of recent works citing this journal's research on Animals, Laboratory, linking to each citing work.