Research Topic · Peer-Reviewed

Splenectomy

Splenectomy is the surgical removal of the spleen, performed either in full (total splenectomy) or in part (partial splenectomy), and undertaken for traumatic, haematological, oncological, and infective indications. The spleen contributes to filtration of senescent and abnormal blood cells, immune surveillance again…

Curated from this journal's research 📚 7 peer-reviewed articles cited Cited 14× across the literature 🔖 ISSN 2578-2371 🗓 Reviewed July 2026

Overview

Splenectomy is the surgical removal of the spleen, performed either in full (total splenectomy) or in part (partial splenectomy), and undertaken for traumatic, haematological, oncological, and infective indications. The spleen contributes to filtration of senescent and abnormal blood cells, immune surveillance against encapsulated organisms, and the clearance of bloodborne pathogens, so its removal carries lasting consequences for immune defence. Common surgical indications include traumatic splenic rupture, sometimes presenting in unusual or massive forms, and space-occupying lesions such as splenic hydatid cysts, including giant and solitary presentations that may require operative excision. Haematological disorders, notably immune thrombocytopenia refractory to medical therapy, represent a major non-traumatic indication, and splenectomy intersects with the diagnosis and treatment strategies for such platelet disorders, including cases following stem-cell transplantation. The spleen's relationship to the portal and gastric venous circulation is also clinically relevant, as splenic and related venous abnormalities can produce complications such as gastric varices. Following splenectomy, patients face an increased lifelong risk of overwhelming infection by encapsulated bacteria, making vaccination, prophylaxis, and patient education central to postoperative care. By relieving mechanical, oncological, and immune-mediated disease, splenectomy remains an important procedure, balanced against the long-term immunological vulnerability that asplenia confers and the need for structured preventive follow-up.

Research published in this journal

7 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2024

Splenectomy Reports

Uluc GünayCorresponding author
Exact topic Spleen And Liver Research doi:10.14302/issn.2578-2371.jslr-24-5157
2015

Giant Isolated Hydatid Cyst of Spleen

Soufi MehdiCorresponding author
Department of digestive Surgery, Faculty of medicine Oujda, University Mohammed first, Oujda -Morocco
Exact topic Spleen And Liver Research Cited by 12 doi:10.14302/issn.2578-2371.jslr-14-543
2021

Solitary Splenic Hydatid Cyst

MERAD ZakariaCorresponding author
Department of pathological anatomy and cytology, Hospital Center of Sidi Bel Abbes, Faculty of Medecine, Djilali Liabes University, 22000, ALGERIA.
Exact topic Clinical and Diagnostic Pathology doi:10.14302/issn.2689-5773.jcdp-21-3890

How this research is being cited

The 7 articles above have been cited 14 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Splenectomy, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Spleen And Liver Research (ISSN 2578-2371).

Journal editorial board
Florin Graur · Romania

This page summarises published research for orientation; it is not medical or professional advice.