Overview
Liver disease is any pathological process that impairs the structure or function of the liver, ranging from reversible injury to end-stage organ failure. Major categories include viral hepatitis, alcohol-related and metabolic (steatotic) liver disease, drug- and toxin-induced injury, autoimmune and cholestatic disorders, and hepatic malignancy. Because the liver controls protein and clotting-factor synthesis, bile secretion, glucose and lipid metabolism, and the clearance of toxins, disease manifests through jaundice, ascites, encephalopathy and coagulopathy and is detected biochemically through aminotransferases and synthetic-function markers. Chronic injury drives a fibrogenic sequence that can culminate in cirrhosis, portal hypertension and hepatocellular carcinoma. Work in this area covers the burden and trends of chronic liver disease in hospital-based cohorts, vitamin D deficiency in chronic liver disease and its clinical significance, genetic polymorphisms associated with fatty liver disease and treatment-related steatosis in HIV, tenofovir treatment of chronic hepatitis B, elastography in portal hypertension, polycystic liver disease, and alcohol-related associations among plasma TREM2, liver enzymes and an MS4A6A polymorphism. Epigenetic and nutritional influences on hepatic health are also represented. The journal publishes peer-reviewed clinical, genetic and experimental research across the breadth of hepatic disease, injury and protection.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Magnitude and Trends of Chronic Liver Disease: A Retrospective Hospital Based Study in Eastern Amhara Region, Northeast Ethiopia
Evaluation of Vitamin D Deficiency in Patients with Chronic Liver Disease and Its Clinical Significance
Single Nucleotide Polymorphisms associated with alimentary fatty liver disease are not genetic risk factors for treatment-associated hepatic steatosis in HIV patients on HAART
Treatment of Chronic Hepatitis B With Tenofovir At The University Teaching Hospital Campus of Lome (Togo)
Pseudotumor Tuberculosis Of Liver: A Rare Entity
Giant Isolated Hydatid Cyst of Spleen
Hepatic Cysts as a Manifestation of Polycystic Kidney Disease (Polycystic Liver Report of 2 Mother-Son Cases)
Liver Stiffness by ARFI does not Correlate with Decompensation and Portal Hypertension in Patients with Cirrhosis
Stratified Analysis of Factors Associated With Mortality in Patients With COVID-19 Based on Cancer and Diabetes
Epigenetics and Nutrition
How this research is being cited
The 12 articles above have been cited 48 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Biochemical Pharmacology
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2026 · Alcohol and Alcoholism
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2026 · BioMed Research International
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Hami Hemati et al. · 2025 · Brain, behavior, and immunity
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2025 · Deleted Journal
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2025 · BMC Gastroenterology
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2025 · BMC Gastroenterology
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Harriet Chinwe Nwadimkpa et al. · 2025 · Discover medicine
A sample of recent works citing this journal's research on Liver Disease, linking to each citing work.