Overview
Obstructive sleep apnea syndrome (OSAS) is a common sleep-related breathing disorder characterized by repeated episodes of partial or complete collapse of the upper airway during sleep, despite ongoing respiratory effort. These obstructive events, apneas and hypopneas, reduce or halt airflow, causing intermittent drops in blood oxygen, surges in carbon dioxide, and brief arousals that fragment sleep, typically without full awakening. The airway collapse arises from anatomical and physiological factors that narrow or destabilize the pharynx during sleep, with risk increased by obesity, craniofacial and soft-tissue features, and certain conditions such as Down syndrome. Hallmark features include loud habitual snoring, witnessed pauses in breathing, choking arousals, and non-restorative sleep, producing excessive daytime sleepiness and reduced quality of life. Through repeated hypoxia, arousal, and sympathetic activation, OSAS is associated with cardiovascular consequences including hypertension, arrhythmia, and increased cardiovascular risk, and it interacts with metabolic disorders such as type 2 diabetes. Diagnosis relies on assessment of symptoms and risk factors together with sleep studies, most definitively polysomnography, that quantify the frequency of respiratory events and associated oxygen desaturation. Management includes weight reduction, positive airway pressure therapy, oral and nasal devices, positional measures, and surgical options in selected cases. Because it is prevalent, often underdiagnosed, and linked to serious health outcomes, OSAS is a central focus of sleep medicine and cardiovascular risk reduction.
Research published in this journal
10 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Obstructive Sleep Apnea in Individuals with Down Syndrome: A Meta-Analytic Literature Review
Assessment of Cardiac Function and Prevalence of Sleep Disordered Breathing using Ambulatory Monitoring with Acoustic Cardiography – Initial Results from SWICOS
Ehlers-Danlos Syndrome and Narcolepsy: An Incidental Relationship?
Obstructive Sleep Apnea Treatment with Epap Nasal Devices: Physiological Principles and Limitations
Assessing the risk of Obstructive Sleep Apnea in Type 2 Diabetes Mellitus patients in India
A Comparison Study of the Fitbit Activity Monitor and PSG for Assessing Sleep Patterns and Movement in Children
Exploring the Endocannabinoid System: From Circadian Rhythms to Sleep Regulation and Potential Therapeutic Insights
Narcolepsy With or Without Cataplexy In The Pediatric Population: A Systematic Review
How to Objectively Measure The Quality of Sleep
How this research is being cited
The 10 articles above have been cited 78 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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Kankanok Attawiboon et al. · 2025 · Siriraj Medical Journal
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V. Vathanophas et al. · 2025 · Congenital Anomalies
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2025 · Congenital Anomalies
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2025 · Elsevier eBooks
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Huỳnh Thiện Duyên Nguyễn et al. · 2025 · Tạp chí Y Dược học Cần Thơ
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Ji-Eun Park et al. · 2024 · Journal of Sleep Medicine
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Fernanda Irrera et al. · 2024 · Italian National Conference on Sensors
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2024 · Cureus
A sample of recent works citing this journal's research on Obstructive Sleep Apnea Syndrome, linking to each citing work.