Overview
Systemic Inflammatory Response Syndrome (SIRS) is a widespread inflammatory condition characterized by the body's exaggerated immune response to various insults, including infection, trauma, or toxins, manifesting through clinical signs such as altered temperature, heart rate, respiratory rate, and white blood cell count. Research published in this journal has examined SIRS across multiple contexts, including experimental models using cecal slurry, lipopolysaccharide, and bacterial challenges in rodents to evaluate inflammatory cytokine responses and the antioxidant and anti-inflammatory effects of proprietary formulations in brain tissues. Additional studies have explored SIRS-related complications in clinical settings, such as assessing vitamin D levels in organophosphorus poisoning patients, evaluating adverse drug reactions in HIV-positive patients receiving antiretroviral therapy, and analyzing risk factors for gastric dilatation-volvulus in veterinary medicine. One investigation examined a myotoxic enzyme from snake venom, relevant to understanding tissue damage and inflammatory cascades. This body of work reflects the syndrome's significance across human and veterinary medicine, where early recognition and understanding of inflammatory mechanisms remain critical for managing diverse pathological conditions that can progress to organ dysfunction and sepsis if untreated.
Research published in this journal
6 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Antioxidant and Anti-Inflammatory Activities of Biofield Energy Treated Proprietary Test Formulation in Brain Tissues in Cecal Slurry, LPS and E. Coli-Induced Systemic Inflammatory Response Syndrome (SIRS) in Sprague Dawley Rats
Clinical Evaluation of Significance of 25(Oh)D Levels in Patients with Organophosphorus Poisoning
Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients
Observations and analysis of risk factors for GDV in a single institution: a case-control study
BaMtox, a Myotoxic Enzyme Isolated from the Venom of the Bothrops Alternatus
How this research is being cited
The 6 articles above have been cited 8 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
-
2024 · Journal of Zoo and Wildlife Medicine
-
2024 · Journal of Complementary and Integrative Medicine
-
Amanda L. Rappaport et al. · 2024 · Journal of zoo and wildlife medicine
-
2024 · Journal of Complementary and Integrative Medicine
-
2022 · ClinicoEconomics and Outcomes Research
-
2021 · Value in Health Regional Issues
-
2020 · International Journal Of Nutrition
-
B. Gupta et al. · 2020 ·
A sample of recent works citing this journal's research on Systemic Inflammatory Response Syndrome, linking to each citing work.