Research Topic · Peer-Reviewed

Muscle Fatigue

Muscle fatigue is a decline in the ability of Skeletal Muscle to generate force or power during or after sustained or repeated activity. It is a normal physiological response to exertion, signaling that the muscle has been working hard, and it usually resolves with rest. Fatigue can arise from processes within the m…

Curated from this journal's research 📚 11 peer-reviewed articles cited Cited 1× across the literature 🔖 ISSN 2832-4048 🗓 Reviewed July 2026

Overview

Muscle fatigue is a decline in the ability of Skeletal Muscle to generate force or power during or after sustained or repeated activity. It is a normal physiological response to exertion, signaling that the muscle has been working hard, and it usually resolves with rest. Fatigue can arise from processes within the muscle itself, such as the depletion of energy substrates, the accumulation of metabolic byproducts, and disturbances in the handling of calcium and other ions that are essential to contraction, as well as from changes in the nervous system's drive to the muscle, often described as central fatigue. The balance of these central and peripheral contributions varies with the type, intensity, and duration of activity. Beyond exercise, persistent or excessive muscle fatigue can reflect overtraining, inadequate nutrition or recovery, or underlying medical conditions, making it relevant to both performance and health. Within the study of Skeletal Muscle, muscle fatigue is examined as a window into the mechanisms of energy supply, contraction, and neuromuscular function, complementing research on muscle structure, strength, and recovery. Understanding fatigue informs approaches to training, rehabilitation, and the maintenance of muscle function across the lifespan. This page gathers definitional and scope context relevant to muscle fatigue within the Skeletal Muscle literature.

Research published in this journal

11 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2020

The Effect of Food Intakes on Musculoskeletal Pains

Nasim Habibzadeh SeyedehCorresponding author
PhD student in Sport Science, School of Health and Life Sine, Department of Sport Science, Teesside University, United Kingdom
Skeletal Muscle doi:10.14302/issn.2832-4048.jsm-20-3519

How this research is being cited

The 11 articles above have been cited 1 time in the scholarly literature. Citation data via OpenAlex and Crossref, updated Oct 2025.

A sample of recent works citing this journal's research on Muscle Fatigue, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Skeletal Muscle (ISSN 2832-4048).

Journal editorial board
Gerhard Meissner · United States Min Du · United States Jeong-Rae Kim · South Korea

This page summarises published research for orientation; it is not medical or professional advice.