Research Topic · Peer-Reviewed

Corticosteroid Therapy

Corticosteroid therapy is the clinical use of glucocorticoid drugs, such as prednisone, methylprednisolone, and dexamethasone, to suppress inflammation and modulate immune responses. These agents act by binding intracellular glucocorticoid receptors and altering the transcription of genes involved in inflammation, r…

Curated from this journal's research 📚 10 peer-reviewed articles cited Cited 44× across the literature 🔖 ISSN 2642-9241 🗓 Reviewed July 2026

Overview

Corticosteroid therapy is the clinical use of glucocorticoid drugs, such as prednisone, methylprednisolone, and dexamethasone, to suppress inflammation and modulate immune responses. These agents act by binding intracellular glucocorticoid receptors and altering the transcription of genes involved in inflammation, reducing the production of cytokines and other mediators and thereby diminishing swelling, pain, and tissue damage. Their broad immunomodulatory action makes them central to the management of autoimmune, allergic, inflammatory, and certain neurological and haematological conditions, though prolonged use carries metabolic, immunosuppressive, and other adverse effects that require careful dosing. Research relevant to this topic includes the timing of immunomodulatory therapy in inflammatory eye disease such as Vogt-Koyanagi-Harada disease, the treatment of immune thrombocytopenia, and the use of corticosteroids in post-infectious neurological disease including acute disseminated encephalomyelitis. Studies of pulse corticosteroid regimens in refractory childhood seizure disorders, and considerations of steroid use in respiratory and post-infectious settings, illustrate the breadth of indications and the balance between benefit and risk. Sub-areas include the pharmacology and mechanism of glucocorticoid action, dosing strategies including pulse therapy, immunosuppression in autoimmune disease, management of adverse effects, and steroid use in respiratory, neurological, and haematological conditions. Corticosteroid therapy remains a versatile but carefully governed tool for controlling inflammation and immune-mediated disease.

Research published in this journal

10 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

A Rare Cause of Acute Renal Failure: Retroperitoneal Fibrosis

Caner EdizCorresponding author
Department of Urology, University of Health Sciences (Istanbul), Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey
Clinical Case Reports and Images doi:10.14302/issn.2641-5518.jcci-19-3098

How this research is being cited

The 10 articles above have been cited 44 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Corticosteroid Therapy, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Respiratory Diseases (ISSN 2642-9241).

Journal editorial board
Jason Akulian · United States

This page summarises published research for orientation; it is not medical or professional advice.