Acute respiratory distress syndrome (ARDS) is a severe, life-threatening form of respiratory failure caused by widespread inflammatory injury to the lungs, in which fluid accumulates in the alveoli and impairs gas exchange, producing profound hypoxaemia. It can be precipitated by direct insults such as pneumonia and…
Acute respiratory distress syndrome (ARDS) is a severe, life-threatening form of respiratory failure caused by widespread inflammatory injury to the lungs, in which fluid accumulates in the alveoli and impairs gas exchange, producing profound hypoxaemia. It can be precipitated by direct insults such as pneumonia and aspiration or by indirect causes including sepsis, trauma and systemic inflammation, and is characterised by the rapid onset of breathlessness, diffuse pulmonary infiltrates and reduced lung compliance. ARDS frequently requires intensive care and mechanical ventilation, and despite supportive management it carries a high risk of organ failure and death. The syndrome attracted renewed attention during the COVID-19 pandemic, when severe SARS-CoV-2 infection emerged as a prominent cause of acute lung injury. Research published in this journal reflects this clinical context, including evaluation of whether the alveolar-arterial oxygen pressure difference can aid diagnosis of ARDS in pneumonia patients, and numerous studies of COVID-19 spanning narrative reviews, cytokine profiling in hospitalised patients, candidate therapies, and post-infectious complications. Additional work considers profiles of patients dying in respiratory-medicine settings and cardiorespiratory monitoring. Together these studies illustrate ongoing interest in the diagnosis, pathophysiology, inflammatory mechanisms and management of acute respiratory failure, particularly in the setting of severe viral and bacterial pneumonia.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 15 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Acute Respiratory Distress Syndrome, linking to each citing work.