Research Topic · Peer-Reviewed

Protein Microarray Analysis

Protein microarray analysis is a high-throughput technique in which large numbers of proteins, antibodies, or other capture molecules are immobilized in an ordered array on a solid surface, allowing the simultaneous study of many protein interactions, abundances, or activities in a single experiment. The platform en…

Curated from this journal's research 📚 7 peer-reviewed articles cited Cited 9× across the literature 🔖 ISSN 2326-0793 🗓 Reviewed July 2026

Overview

Protein microarray analysis is a high-throughput technique in which large numbers of proteins, antibodies, or other capture molecules are immobilized in an ordered array on a solid surface, allowing the simultaneous study of many protein interactions, abundances, or activities in a single experiment. The platform enables miniaturized, parallel detection and is used to profile protein expression, map binding partners, screen for biomarkers, and characterize enzymatic and post-translational activity. Common formats include analytical or antibody arrays for measuring specific proteins in complex samples, functional arrays of purified proteins for studying interactions and modifications, and reverse-phase arrays for quantifying targets across many samples. As a component of proteomics, protein microarray analysis complements mass-spectrometry-based approaches such as quantitative proteomics using stable-isotope labelling, together building the protein inventories and interaction maps central to efforts like the human proteome project. The technology supports investigation of signalling and regulatory proteins, including the study of molecules such as optineurin in the control of chemokines and kinases, and the dissection of disease-related pathways, for example regulatory mechanisms in colorectal cancer. By revealing patterns of protein expression and interaction, it informs biomarker discovery, disease diagnosis, and drug development. Protein microarray analysis thus provides a scalable means of surveying the proteome, linking protein abundance and function to biological state and supporting both basic research and translational applications in disease characterization.

Research published in this journal

7 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2013

Quantitative Proteomics Using 15N SILAC Mouse

I. Chen EmilyCorresponding author
Stony Brook University, Proteomics Center, School Of Medicine, NY
Proteomics and Genomics Research Cited by 4 doi:10.14302/issn.2326-0793.jpgr-13-252
2016

GR-RNF43 Regulation in Colorectal Cancer

Chan ChristinaCorresponding author
Cell and Molecular Biology Program, Michigan State University, 567 Wilson Road, Rm 2240A, East Lansing, Michigan 48824, USA
Proteomics and Genomics Research Cited by 1 doi:10.14302/issn.2326-0793.jpgr-16-941

How this research is being cited

The 7 articles above have been cited 9 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Protein Microarray Analysis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Proteomics and Genomics Research (ISSN 2326-0793).

Journal editorial board
Sutopa Dwivedi · United States Liuyang Wang · United States Juan Sainz · Spain

This page summarises published research for orientation; it is not medical or professional advice.