Research Topic · Peer-Reviewed

Protein Identification

Protein identification is the process of determining which proteins are present in a biological sample, a foundational task in proteomics that links the complex mixtures of cellular proteins to their underlying gene products and functions. Proteins are large biomolecules that provide structure, catalyze reactions, a…

Curated from this journal's research 📚 10 peer-reviewed articles cited Cited 61× across the literature 🔖 ISSN 2326-0793 🗓 Reviewed July 2026

Overview

Protein identification is the process of determining which proteins are present in a biological sample, a foundational task in proteomics that links the complex mixtures of cellular proteins to their underlying gene products and functions. Proteins are large biomolecules that provide structure, catalyze reactions, and transport and regulate molecules within cells, and identifying them reveals how the proteome varies with cell type, condition, and disease. The dominant analytical approach is mass spectrometry, in which proteins are typically digested into peptides whose mass and fragmentation spectra are measured and matched against sequence databases to infer identity. Strategies include shotgun and label-free proteomics for broad profiling, ion-current-based and targeted quantitative methods that compare protein abundance between states such as drug treatment, and affinity purification coupled with tandem mass spectrometry to characterize interacting proteins. These methods support the study of protein function, post-translational modification, and interaction networks, and they underpin large-scale efforts such as the Human Proteome Project and bioinformatic analyses that connect proteins to disease pathways. Accurate identification depends on sample preparation, instrument performance, reproducible workflows, and computational analysis of spectra. By revealing the identities and quantities of proteins in samples ranging from human tissue to parasites and model systems, protein identification advances biomarker discovery, mechanistic biology, and the diagnosis and treatment of disease.

Research published in this journal

10 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

Shotgun Label-Free Proteomic Analyses of the Oyster Parasite Perkinsus Marinus

C. P. Figueiredo HenriqueCorresponding author
AQUACEN, National Reference Laboratory for Aquatic Animal Diseases, Ministry of Agriculture, Livestock and Food Supply, Federal University of Minas Gerais, Belo Horizonte, Brazil
Exact topic Proteomics and Genomics Research Cited by 11 doi:10.14302/issn.2326-0793.JPGR-17-1571

How this research is being cited

The 10 articles above have been cited 61 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Protein Identification, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Proteomics and Genomics Research (ISSN 2326-0793).

Journal editorial board
Sutopa Dwivedi · United States Liuyang Wang · United States Juan Sainz · Spain

This page summarises published research for orientation; it is not medical or professional advice.