DNA-protein interactions refer to the physical and functional associations between deoxyribonucleic acid sequences and protein molecules, which are fundamental to gene regulation, chromatin structure, and cellular function. Research published in Proteomics and Genomics Research addresses multiple dimensions of this …
DNA-protein interactions refer to the physical and functional associations between deoxyribonucleic acid sequences and protein molecules, which are fundamental to gene regulation, chromatin structure, and cellular function. Research published in Proteomics and Genomics Research addresses multiple dimensions of this topic, including bioinformatic analyses that link genetic variants to protein function in disease contexts such as coronary atherosclerosis and high-altitude adaptation. The journal has featured studies examining transcription factor binding sites at regulatory single nucleotide polymorphisms, demonstrating how sequence variations influence protein recruitment and gene expression patterns. Methodological advances in affinity purification coupled with tandem mass spectrometry have enabled researchers to identify protein complexes and interaction networks in mammalian cells. Additional work has explored how genetic polymorphisms in genes encoding proteins like angiotensin-converting enzyme correlate with disease phenotypes across populations. The journal also covers broader applications of integrated proteomic and genomic techniques in cancer research, diagnostics, and personalized medicine, as well as computational approaches to understanding how DNA sequence elements determine protein binding specificity. These investigations collectively illuminate how DNA-protein interactions mediate normal physiology and contribute to disease pathogenesis, informing both basic biological understanding and translational research efforts.
11 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 11 articles above have been cited 87 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on DNA - Protein Interactions, linking to each citing work.