Research Topic · Peer-Reviewed

Peptide Synthesis

Peptide synthesis is the process of chemically constructing Peptides, short chains of amino acids joined by peptide bonds, by linking individual amino acids together in a defined sequence. The dominant approach is solid-phase peptide synthesis, in which the growing chain is anchored to an insoluble support and amino…

Curated from this journal's research 📚 4 peer-reviewed articles cited Cited 2× across the literature 🗓 Reviewed July 2026

Overview

Peptide synthesis is the process of chemically constructing Peptides, short chains of amino acids joined by peptide bonds, by linking individual amino acids together in a defined sequence. The dominant approach is solid-phase peptide synthesis, in which the growing chain is anchored to an insoluble support and amino acids are added stepwise through cycles of coupling and deprotection, with reactive side chains masked by protecting groups to ensure that bonds form only where intended. Careful control of these steps allows Peptides of precise sequence and structure to be assembled, after which they are cleaved from the support and purified. Synthetic Peptides are widely used in pharmaceutical research and the development of therapeutic agents, as well as in studies of protein structure and function and in the design of vaccines and diagnostics. Research published in the journal Peptides reflects active methodological work in this area, including the synthesis of Peptides in aqueous solution using a reusable solid phase, strategies for protecting the side chain of lysine with host-affinity molecules during aqueous-phase solid-phase synthesis, and methods using Peptides to block hydrophobic interactions and inhibit amyloid formation. This page gathers peer-reviewed, open-access research relevant to peptide chemistry and synthesis.

Research published in this journal

4 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

Template Independent Synthesis of Nucleic Acid Libraries

D. Bhilare KiranCorresponding author
Biocatalysis and Protein Engineering Group, Department of Pharmaceutical Technology (Biotechnology), National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab, India
DNA And RNA Research Cited by 2 doi:10.14302/issn.2575-7881.jdrr-17-1749

How this research is being cited

The 4 articles above have been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Peptide Synthesis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Peptides.

Journal editorial board
Laura Zaccaro · Italy Emilia Pedone · Italy Dulari Jayawardena · United States

This page summarises published research for orientation; it is not medical or professional advice.