Research Topic · Peer-Reviewed

Graves Disease

Graves' disease is an autoimmune disorder of the thyroid gland and the most common cause of hyperthyroidism, in which autoantibodies directed against the thyroid-stimulating hormone receptor mimic the action of the hormone and drive unregulated synthesis and release of thyroid hormones. The resulting thyrotoxicosis …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 46× across the literature 🔖 ISSN 2379-8572 🗓 Reviewed July 2026

Overview

Graves' disease is an autoimmune disorder of the thyroid gland and the most common cause of hyperthyroidism, in which autoantibodies directed against the thyroid-stimulating hormone receptor mimic the action of the hormone and drive unregulated synthesis and release of thyroid hormones. The resulting thyrotoxicosis produces signs and symptoms such as weight loss despite increased appetite, palpitations and tachycardia, heat intolerance, sweating, tremor, anxiety, and a diffuse goitre. The disease is distinguished by extrathyroidal manifestations, notably Graves' orbitopathy with proptosis and ophthalmic involvement, and less commonly pretibial dermopathy, reflecting the shared autoimmune target in orbital and dermal tissue. Diagnosis rests on the clinical picture together with suppressed thyroid-stimulating hormone, elevated free thyroid hormones, and detectable stimulating autoantibodies, supported by imaging and uptake studies. Management options include antithyroid medication, radioactive iodine ablation, and surgery, each balancing control of hyperthyroidism against the risk of subsequent hypothyroidism, alongside specific treatment of orbitopathy. As an organ-specific autoimmune condition, Graves' disease intersects endocrinology, immunology, and otolaryngology, given its effects on the neck and thyroid. The journal publishes peer-reviewed research relevant to thyroid disease, including disorders of thyroid function and the structural and functional abnormalities of the thyroid gland.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 46 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Graves Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Otolaryngology Advances (ISSN 2379-8572).

Journal editorial board
Ioannis Chatzistefanou · Greece Heather Bortfeld · United States Heidi Silver · United States

This page summarises published research for orientation; it is not medical or professional advice.