Research Topic · Peer-Reviewed

Retinal Vein Occlusion

Retinal vein occlusion (RVO) is a common retinal vascular disorder caused by thrombotic blockage of a vein draining the retina, leading to raised venous pressure, haemorrhage, retinal oedema, and ischaemia that can impair vision. It is classified by the site of obstruction into central retinal vein occlusion (CRVO),…

Curated from this journal's research 📚 7 peer-reviewed articles cited Cited 22× across the literature 🔖 ISSN 2470-0436 🗓 Reviewed July 2026

Overview

Retinal vein occlusion (RVO) is a common retinal vascular disorder caused by thrombotic blockage of a vein draining the retina, leading to raised venous pressure, haemorrhage, retinal oedema, and ischaemia that can impair vision. It is classified by the site of obstruction into central retinal vein occlusion (CRVO), affecting the main vein at the optic nerve head, and branch retinal vein occlusion (BRVO), affecting a tributary vein, usually at an arteriovenous crossing. Vision loss results chiefly from macular oedema and, in ischaemic forms, from retinal and anterior-segment neovascularization. Established risk factors include hypertension, diabetes, and thrombophilic and hypercoagulable states. This topic spans the presentation, systemic associations, and management of RVO. Relevant work documents central retinal vein occlusion arising in the setting of hepatocellular carcinoma and branch retinal vein occlusion associated with a Factor V Leiden mutation, illustrating links to underlying systemic and prothrombotic disease. Related research examines occlusive events tied to plasminogen-activator-inhibitor mutations and compares treatment strategies, including combined anti-vascular endothelial growth factor (anti-VEGF) therapy with corticosteroids versus anti-VEGF alone for the resulting macular oedema. Together these studies underscore the value of evaluating systemic risk factors alongside ophthalmic treatment of the retinal complications.

Research published in this journal

7 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 7 articles above have been cited 22 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Retinal Vein Occlusion, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Ophthalmic Science (ISSN 2470-0436).

Journal editorial board
Argyrios Tzamalis · GREECE Brian M. DeBroff · United States Emanuela Interlandi · Italy

This page summarises published research for orientation; it is not medical or professional advice.