Research Topic · Peer-Reviewed

Macular Hole Surgery

Macular hole surgery is the vitreoretinal procedure used to close a full-thickness defect in the macula, the central region of the retina responsible for detailed central vision. A macular hole develops most often from tangential and anteroposterior traction exerted by the vitreous and the internal limiting membrane…

Curated from this journal's research 📚 8 peer-reviewed articles cited Cited 52× across the literature 🔖 ISSN 2470-0436 🗓 Reviewed July 2026

Overview

Macular hole surgery is the vitreoretinal procedure used to close a full-thickness defect in the macula, the central region of the retina responsible for detailed central vision. A macular hole develops most often from tangential and anteroposterior traction exerted by the vitreous and the internal limiting membrane at the foveal centre, producing a break that causes central blurring, distortion (metamorphopsia), and a central scotoma. Optical coherence tomography is the principal tool for diagnosis and staging, defining hole size and configuration, which guide surgical planning and prognosis. The standard operation is pars plana vitrectomy, in which the vitreous is removed to relieve traction; this is typically combined with peeling of the internal limiting membrane to release residual tangential forces and promote closure. The eye is then filled with a gas or air tamponade, and postoperative positioning, often face-down, helps appose the hole margins while it seals. Anatomical closure rates are generally high, with visual recovery influenced by hole size, chronicity, and macular health. Variations in technique, including adjuncts for large or persistent holes, continue to be refined. As a representative example of modern vitreoretinal microsurgery, macular hole surgery illustrates how relieving mechanical traction and providing tamponade can restore foveal architecture and improve central vision.

Research published in this journal

8 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

Femtosecond Laser in Cataract Surgery: What Makes it Worth it? or not?

Stonecipher KarlCorresponding author
Clinical Associate Professor of Ophthalmology, University of North Carolina, Medical Director, The Laser Center, Greensboro, North Carolina, Medical Director, Physicians Protocol, Medical Director, Laser Defined Vision
Ophthalmic Science doi:10.14302/issn.2470-0436.jos-18-2494

How this research is being cited

The 8 articles above have been cited 52 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Macular Hole Surgery, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Ophthalmic Science (ISSN 2470-0436).

Journal editorial board
Argyrios Tzamalis · GREECE Brian M. DeBroff · United States Emanuela Interlandi · Italy

This page summarises published research for orientation; it is not medical or professional advice.