Depression And Therapy
Open Access
Basal Serum Cortisol Levels, Depression and Medial Temporal Lobe Atrophy in Patients with Mild Cognitive Impairment and Alzheimer’s Disease
Mar 2016 DOI 10.14302/issn.2476-1710.jdt-15-719
Dhikav VikasCorresponding author
Postgraduate Institute of Medical Education & Research & Dr. Ram Manohar Lohia Hospital, New Delhi, INDIA
This clinical study explores associations among basal serum cortisol, depressive symptoms, and medial temporal lobe atrophy in patients with MCI and Alzheimer's disease. It discusses stress‑axis dysregulation as a potential contributor to neurodegeneration and outlines implications for assessment and intervention.