Search results for “Bridge

About 8 results in articles

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8 articles

Proteomic and Genomic Techniques in Medical Research: Applications in Cancer, Diagnostics, and Personalized Medicine

Nov 2025 DOI 10.14302/issn.2326-0793.jpgr-25-5573
E. Imiruaye OghenetegaCorresponding author

Advancements in proteomic and genomic technologies have transformed molecular biology by enabling comprehensive analysis of biological systems at the molecular level. This literature review explores the evolution, methodologies, and practical applications of key proteomic and genomic techniques. In proteomics, tools such as two-dimensional electrophoresis, mass spectrometry, Western blotting, Edman degradation, and functional protein microarrays have facilitated high-throughput protein identification, post-translational modification analysis, and biomarker discovery. Similarly, genomic methodologies like PCR, recombinant DNA technology, gel electrophoresis, and Southern blotting have revolutionized gene detection, manipulation, and expression profiling. The review also highlights the interdisciplinary impact of these technologies across clinical diagnostics, oncology, autoimmune disorders, infectious disease surveillance, cardiovascular research, and personalized nutrition. Integrative approaches combining proteomics and genomics are enabling the discovery of novel therapeutic targets, improving disease classification, and advancing precision medicine. Despite current limitations, such as the absence of amplification techniques for proteins and challenges in data interpretation, ongoing innovations promise to bridge these gaps. This synthesis underscores the pivotal role of molecular techniques in deepening our understanding of human biology and accelerating biomedical advancements for improved healthcare outcomes.

Agronomy Research Open Access

Effect of Nitrogen Fertilizer and Plant Spacing on Vegetative Growth of Sugar Beet (Beta vulgaris)

Aug 2021 DOI 10.14302/issn.2639-3166.jar-21-3883
Haroun Mohamed Adam AbubakerCorresponding author Department of Crop Science, College of Agriculture, University of Bahri- Sudan.

Despite the existing several Sugar manufacturing companies in Sudan, there is an acute shortage in sugar supply, therefore the government imports Sugar to bridge the gap. One of the strategies to be followed is the introduction of Sugar beet (Beta vulgaris) crop, mainly for sugar production. This crop has several advantages over Sugarcane such as short duration, less water requirement, in addition to other uses like animal feed. Therefore it became necessary to have good understanding of agricultural operations, cultural practices and adaptation. However, the main objective of this study was to assess the effect of Nitrogen fertilizer and plant spacing on vegetative growth of Sugar beet. This study was conducted at the farm of the College of Agriculture, University of Bahri, Alkadro, Khartoum State-Sudan; during the season 2016/2017. The experiment was arranged in Split plot in Randomized Complete Block Design with six treatments and four replications. Two plant spacing (15 and 20 cm.) were used as main plot, referred as (S1, S2) along with three levels of Nitrogen fertilizer (40, 80 and 120 kg/ha.), as subplot; referred as (N1, N2 and N3) and the control (0). Data regarding leaf number, leaf area index (LAI), leaf dry weight (g) (LDW), root diameter (mm.) and root fresh weight were recorded and statistically analyzed. The results showed S2 (20 cm) increased all the studied plant characters, namely the leaf number (29.139), leaf area index by (7.54), leaf dry weight (g) to (89.870), root diameter (mm) (94,992), root fresh weight (g) (695.80) compared to S1(1015 cm). On the other hand; the application of N3 (120 kg/ha.) increased the lead number (30.956), leaf Area Index (8.841), Leaf dry weight (102.47), root diameter (97.955) and root fresh weight (851.77) compared to S2 and S1 as presented in (table 4, table 5 and table 6).

Basic Sciences. Basis of Clinical Medicine.

Nov 2018 DOI 10.14302/issn.2578-8590.ipj-18-2490
Hinzpeter JaimeCorresponding author Medical Doctor, University of Chile, Clinical Hospital, Santiago Chile

A short editorial underscores the bridge between basic sciences and clinical medicine. It emphasizes how mechanistic knowledge informs diagnostics and therapy, and calls for curricula that strengthen this continuum.

Water Open Access

On Filtration in a Rectangular Interchange with a particularly Unpermatable Vertical wall in the Evaporation

Nov 2018 DOI 10.14302/issn.2769-2264.jw-18-2393
Bireslavskii E.N.Corresponding author Department of Applied Mathematics and Informatics, University of Civil Aviation, St. Petersburg, Russia

We consider a plane steady-state filtration in a rectangular bridge with a partially impermeable vertical wall in the presence of evaporation from a free surface of groundwater. To study the effect of evaporation, a mixed multiparametric boundary-value problem of the theory of analytic functions is formulated and using the method of P. Y. Polubarinova-Kochina. Based on the proposed model, an algorithm is developed to calculate the dependence of efficiency and productivity of hydrodynamic analysis.

Human Health Research Open Access

An Urgent Human Health Dilemma Facing Refugees and their Host Caregivers?

May 2018 DOI 10.14302/issn.2576-9383.jhhr-18-2111
Silbermann MichaelCorresponding author Middle East Cancer Consortium (MECC)

The continuous waves of refugees from Africa and the Middle East to Europe present major inter¬cultural challenges to European health professionals and to society at large. A recent workshop in Sicily brought together local physicians, nurses, psychologists and managers of governmental agencies, along with representatives from Lebanon, Israel, Iraq, Iran, Sudan, Tunisia, Jordan and the European Society of Medical Oncology (ESMO) to develop training programs aimed at formulating dialogue between regional professionals and refugees. A major barrier refugees face is a lack of verbal and cultural communication, which hinders their smooth absorption into the new society. Cultural mediators who speak Arabic and Italian and understand the refugees' faith, tradition and beliefs are vital to successfully build bridges of trust between caregivers and refugees. Most asylum seekers experience anxiety, fear, and depression upon arrival in Europe. To achieve trust, all workshop participants agreed to develop a palliative care model that would best suit the unique circumstances now facing some Mediterranean countries and assist in overcoming the suffering of refugees during their initial stay in Europe. Such a model would include bio-psychosocial elements, essential for a culturally sensitive approach and based on core ethical principles.

Social Work in Psychosocial Crises: Analysis of a Voluntary Psychosocial Counseling Program to Close a Supply Gap in Psychosocial Therapy

Jan 2017 DOI 10.14302/issn.2474-3585.jpmc-16-1325
Franke AndreasCorresponding author University of Applied Sciences Neubrandenburg

Background: People suffering from acute psychosocial crises often require immediate help. To supplement existing institutions and services, a counseling program (“Hel.p”) was founded; this study evaluates that program following a two-year trial period. Methods: The program offered anonymous, free-of-charge appointments to the public conducted by consultants holding, at minimum, a bachelor’s degree in social work. Supervised by a judge and a psychologist, client-centered counseling sessions were conducted each week. Results: Thirty-five counselors counseled 70 people. The clients were 37.6 +/- 18.4 years old and mostly female (67.1%). The counseling topics included health and diseases (16.1%) and general family problems (11.3%). The majority of the sessions (63.5%) took place during acute psychosocial crises. Conclusions: “Hel.p” functions as a supplement to established outreach clinics for people with acute psychosocial crises. It bridges the gap between individuals’ acute psychosocial problems and the delayed psychiatric/psychotherapeutic treatment caused by resource restrictions in the health care system.

Fostering Partnerships between Public Health Functions within Health and Social Services Organizations: A Perspective from the Province of Quebec (Canada)

Sep 2016 DOI 10.14302/issn.2474-3585.jpmc-16-1106
Roy MathieuCorresponding author Department of Family Medicine and Emergency Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, (Québec, Canada)

Health and social services organizations discriminate too much between core public health functions. Health protection actions, services, and programs are often separate from those concerned with disease prevention and health promotion. In this comment, we advocate for more partnerships between all public health functions within health and social services organizations. Stronger bridges between such teams, services, and programs are needed to move forward with a more encompassing and integrated perspective aiming for social justice and equity. In this comment, we support this position with some examples. We also use smoking-related issues from a regional representative population-based sample (Eastern Townships, Quebec, Canada) to demonstrate how we can better struggle against social inequalities with a perspective that simultaneously considers all functions of public health within actions, services, and programs of health and social services organizations. We conclude with avenues to foster such partnerships.

A Forum Bridging Between Basic and Translational Research

Jan 2013 DOI 10.14302/issn.2328-0182.japst-13-edt-1.1
Qin SuofuCorresponding author Retinal Disease Research, Department Of Biological Sciences, Allergan, Inc., 2525 Dupont Drive, Irvine, CA 92612.

This inaugural editorial introduces a forum that bridges basic discovery and translational application across pharmaceutical science and technology. It emphasizes rapid, open‑access dissemination paired with rigorous peer review to shorten the bench‑to‑bedside path. The journal invites interdisciplinary submissions that highlight novel methods, materials, and clinically actionable findings.

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