Dyslipidemia is an abnormality in the concentration or composition of plasma lipids and lipoproteins, encompassing elevated low-density lipoprotein (LDL) cholesterol, elevated triglycerides, reduced high-density lipoprotein (HDL) cholesterol, or combinations thereof. It may be primary, reflecting genetic determinant…
Dyslipidemia is an abnormality in the concentration or composition of plasma lipids and lipoproteins, encompassing elevated low-density lipoprotein (LDL) cholesterol, elevated triglycerides, reduced high-density lipoprotein (HDL) cholesterol, or combinations thereof. It may be primary, reflecting genetic determinants of lipid metabolism, or secondary to obesity, type 2 diabetes, insulin resistance, diet, and sedentary behavior, and it frequently coexists within the metabolic syndrome. Atherogenic dyslipidemia—high triglycerides with low HDL and small dense LDL particles—is a principal driver of atherosclerosis and a major modifiable risk factor for coronary artery disease, myocardial infarction, and stroke. Genetic factors, including polymorphisms in the vitamin D receptor and lipid-regulatory genes, modulate susceptibility. Diagnosis rests on the lipid profile, and management combines dietary change, weight loss, and exercise with lipid-lowering pharmacotherapy such as statins, alongside dietary fatty acids and nutraceuticals under study. Research relevant to this area examines vitamin D receptor polymorphisms associated with dyslipidemia in coronary artery disease, lipid responses to obesity and protein-supplementation interventions, chronic-disease risk factors in vegetarian and dietary cohorts, antioxidant micronutrients in metabolic syndrome, and the effects of omega-3 fatty acids on serum triglycerides. This peer-reviewed literature reflects the genetic, dietary, and pharmacologic dimensions of disordered blood lipids within the broader study of cardiometabolic risk and Obesity Management.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 36 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Dyslipidemia, linking to each citing work.