Overview
Column chromatography is a laboratory technique used to separate and purify the components of a mixture based on their differing interactions with a stationary phase and a mobile phase. A column is packed with a solid stationary material, and the mixture is passed through it dissolved in a liquid or carried by a solvent; as the components travel down the column at different rates according to their physical and chemical properties, they separate into distinct bands and can be collected individually. It is a fundamental and widely used method in organic, analytical, and pharmaceutical chemistry for isolating compounds and removing impurities. Research in this subject area applies chromatographic separation and purification to chemical synthesis and analysis. Studies have used these methods in the synthesis and purification of glycosyl and nucleoside compounds, the isolation and characterization of enzymes such as xanthine oxidase and peroxidase, and the separation of bioactive compounds from natural sources. This page gathers peer-reviewed, open-access research relevant to column chromatography and its role in the separation, purification, and analysis of chemical compounds in the broader study of New Developments in Chemistry.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Syntheses of Clofarabine and Related C2′-β-fluorinated Nucleoside Analogues
Synthesis of 2-Chloro-2′-Deoxyadenosine (Cladribine) and New Purine Modified Analogues
Stereoselective Synthesis of N-Glycosyl Oxazolines and Evaluation of Their Antiproliferative Activity
Purification and Characterization of Xanthine Oxidase from Liver of the Sheep (Ovis Aries)
Antibacterial and Cytotoxicity Activities of Major Compounds from Tinospora cordifolia Willd. Growing on Mangifera indica L.
Peroxidase from Coleus Forskohlii: Purification and Biochemical Characterization
Identification and Quantification of an Adulterant in a Dietary Supplement Marketed for Sexual Enhancement
Effects of Selected Secondary Metabolites in Leaf Extract of Jatropha Tanjorensis on Some Gonadal Hormones in Male Wistar Rats
Preparation and Application for Separation of Small Molecules of a New Poly(OVS-co-EDMA) Hybrid Monolithic Column
Liquid Chromatography Tandem Mass Spectrometry Method for Determination of Febuxostat in Human Plasma to Support A Bioequivalence Study
Liquid Chromatography-Mass Spectrometry (LC-MS) Applications in Food Safety–Review
How this research is being cited
The 12 articles above have been cited 64 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Current Microbiology
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2025 · Separation and Purification Technology
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2025 · International Journal of Biological Macromolecules
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2025 · International Journal of Biological Macromolecules
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2025 · Journal of New Developments in Chemistry
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2025 · Journal of new developments in Chemistry
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2025 · Separation and Purification Technology
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2025 · The Natural Products Journal
A sample of recent works citing this journal's research on Column Chromatography, linking to each citing work.