Overview
Addition reactions are chemical transformations in which two or more molecules combine to form a single product, typically involving the conversion of multiple bonds into single bonds. Research published in New Developments in Chemistry on this topic has focused on addition reactions involving carbohydrate substrates, particularly in the synthesis of nitrogen-containing glycosyl derivatives. Published work has examined stereoselective approaches to N-glycosyl oxazoline formation, where addition reactions create heterocyclic rings with defined three-dimensional configurations, and has evaluated the biological properties of the resulting compounds. Additional studies have explored both the hydrolysis of protected glycosyl oxazolines and Ritter-like addition reactions using native carbohydrates to produce N-glycosyl amides. These investigations demonstrate how addition reactions can be applied to modify carbohydrate structures in controlled ways, creating compounds with potential applications in medicinal chemistry. The work illustrates the continuing importance of addition reactions as fundamental synthetic tools for constructing complex molecules with specific stereochemical outcomes, particularly in the context of carbohydrate chemistry where precise control over molecular architecture is essential for biological activity.
Research published in this journal
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Synthesis of N-Glycosyl Amides via Hydrolysis of Protected Glycosyl Oxazolines and Ritter-like Reactions of Native Carbohydrates
How this research is being cited
The 2 articles above have been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · Journal of New Developments in Chemistry
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2025 · Journal of new developments in Chemistry
A sample of recent works citing this journal's research on Addition Reactions, linking to each citing work.