Research Topic · Peer-Reviewed

Brain Inflammation

Brain inflammation, or neuroinflammation, refers to the activation of the brain's immune response, typically involving the release of inflammatory molecules such as cytokines and the recruitment of immune cells in response to injury, infection, or disease. Research published in Neurological Research and Therapy addr…

Curated from this journal's research 📚 10 peer-reviewed articles cited Cited 19× across the literature 🔖 ISSN 2470-5020 🗓 Reviewed July 2026

Overview

Brain inflammation, or neuroinflammation, refers to the activation of the brain's immune response, typically involving the release of inflammatory molecules such as cytokines and the recruitment of immune cells in response to injury, infection, or disease. Research published in Neurological Research and Therapy addresses multiple dimensions of this phenomenon across diverse neurological conditions. Published studies examine proinflammatory cytokines including interleukin-6 and tumor necrosis factor-alpha in experimental models, exploring how dietary deficiencies and potential therapeutic interventions may modulate inflammatory markers in brain tissue. The journal has documented inflammation's role in post-infectious neurological complications, including acute disseminated encephalomyelitis following viral illness, and investigated oxidative stress and inflammatory pathways in neurotoxic exposures affecting the hippocampus. Additional work explores the theoretical frameworks connecting inflammation to autism spectrum disorder pathophysiology, the potential of neuromodulation approaches for neurodegenerative conditions where inflammation plays a role, and clinical outcomes in traumatic brain injury where inflammatory cascades contribute to secondary damage. This research underscores that brain inflammation represents a common pathway in numerous neurological disorders, making it a critical target for understanding disease mechanisms and developing interventions across pediatric and adult populations.

Research published in this journal

10 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2021
2019

Neuroscience Theories, Hypothesis and Approaches to ASD Physiopathology. A Review

OJ CastejónCorresponding author
Instituto de Investigaciones Biológicas “Drs. Orlando Castejón and Haydee Viloria de Castejón” e Instituto de Neurociencias Clínicas, Fundación Castejón, San Rafael Clinical Home. Maracaibo. Venezuela.
Neurological Research and Therapy Cited by 2 doi:10.14302/issn.2470-5020.jnrt-19-2974

How this research is being cited

The 10 articles above have been cited 19 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Brain Inflammation, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Neurological Research and Therapy (ISSN 2470-5020).

Journal editorial board
Ian J Martins · Australia Giuseppe Lanza · Italy Ion Codreanu · United States

This page summarises published research for orientation; it is not medical or professional advice.