Renal failure is a condition in which the kidneys lose their ability to adequately filter waste products and excess fluid from the blood, leading to the accumulation of toxins and disturbances in fluid, electrolyte, and acid-base balance. Renal failure may develop suddenly (acute kidney injury) or progress gradually…
Renal failure is a condition in which the kidneys lose their ability to adequately filter waste products and excess fluid from the blood, leading to the accumulation of toxins and disturbances in fluid, electrolyte, and acid-base balance. Renal failure may develop suddenly (acute kidney injury) or progress gradually (chronic kidney disease), and it is a major focus of nephrology because of its links to common conditions such as diabetes, hypertension, infections, and immune disorders. Impaired kidney function affects multiple organ systems and, in advanced stages, requires interventions such as dialysis or transplantation. Understanding its causes, mechanisms of injury, and management is central to preventing progression and complications. Research collected here reflects these concerns across the spectrum of kidney disease, including the nephrotoxicity of iodinated radiographic contrast agents, acute renal failure due to retroperitoneal fibrosis, and dietary or intestinal-dialysis approaches to chronic renal failure. Additional studies examine the mechanisms and therapeutic targets of renal fibrosis, hypertension patterns by chronic kidney disease stage, oxidative stress and inflammatory markers in maintenance hemodialysis patients, thyroid function abnormalities in chronic kidney disease, polycystic kidney disease, refractory anemia, and cardiorenal signaling in heart failure. Together these themes illustrate renal failure as a clinical and research area spanning its causes, systemic consequences, fibrotic progression, and treatment.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 73 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Renal Failure, linking to each citing work.