Research Topic · Peer-Reviewed

Physiology & Pathophysiology of Renal Diseases

Physiology and pathophysiology of renal diseases encompass the normal functioning of the kidneys and the mechanisms by which disease processes disrupt these functions, leading to impaired filtration, electrolyte imbalance, and progressive organ damage. Research published in Nephrology Advances addresses several dime…

Curated from this journal's research 📚 3 peer-reviewed articles cited Cited 32× across the literature 🔖 ISSN 2574-4488 🗓 Reviewed July 2026

Overview

Physiology and pathophysiology of renal diseases encompass the normal functioning of the kidneys and the mechanisms by which disease processes disrupt these functions, leading to impaired filtration, electrolyte imbalance, and progressive organ damage. Research published in Nephrology Advances addresses several dimensions of this field, including the molecular mechanisms underlying renal fibrosis and the identification of therapeutic targets to prevent progressive scarring of kidney tissue. The journal has examined immune-mediated glomerular diseases, specifically documenting cases where membranous nephropathy experiences disease flares following immunological triggers such as vaccination. Additionally, investigations have explored potential cardioprotective and renoprotective interventions in experimental models of hypertension and metabolic dysfunction induced by dietary factors and pharmacological agents. Understanding renal pathophysiology is essential because kidney diseases affect millions globally, often progressing silently until significant function is lost, and because the kidneys' role in maintaining homeostasis means their dysfunction has systemic consequences affecting cardiovascular health, bone metabolism, and overall survival. Identifying the cellular and molecular pathways that drive disease progression remains critical for developing targeted therapies that can slow or reverse kidney damage before patients require dialysis or transplantation.

Research published in this journal

3 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 3 articles above have been cited 32 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Physiology & Pathophysiology of Renal Diseases, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Nephrology Advances (ISSN 2574-4488).

Journal editorial board
Ying-Yong Zhao · United States Santiago Cuevas · United States Istvan Arany · United States

This page summarises published research for orientation; it is not medical or professional advice.