Kidney disease is a condition in which the kidneys are damaged and progressively lose their ability to filter waste and excess fluid from the blood, often developing silently until advanced stages and contributing to complications such as anemia, hypertension, and cardiovascular disease. Kidney disease, frequently c…
Kidney disease is a condition in which the kidneys are damaged and progressively lose their ability to filter waste and excess fluid from the blood, often developing silently until advanced stages and contributing to complications such as anemia, hypertension, and cardiovascular disease. Kidney disease, frequently chronic in nature, is a major focus of nephrology because of its high prevalence and its close relationship with diabetes, high blood pressure, and other systemic disorders. As kidney function declines, the body retains waste products and fluid and develops disturbances in electrolytes, blood pressure, and red-blood-cell production, making early detection and management essential to slow progression and prevent end-stage disease. Research and care address diagnosis, staging, risk factors, and the systemic effects of impaired kidney function. Studies gathered here reflect these themes, including polycystic kidney disease, thyroid function abnormalities and morphological thyroid changes in chronic and end-stage kidney disease, and hypertension patterns analyzed by chronic kidney disease stage. Additional work examines reductions in estimated glomerular filtration rate with elevated blood urea nitrogen, distinguishing depression from apathy in chronic kidney disease, the toxicity of iodinated radiographic contrast agents, the role of BCL-2 and BAK genes and of hepcidin gene polymorphisms in kidney disease and hemodialysis patients, renal fibrosis mechanisms and therapeutic targets, oxidative and inflammatory markers in hemodialysis, and cardiorenal signaling in heart failure, illustrating the clinical and molecular breadth of kidney disease.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 86 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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