Research Topic · Peer-Reviewed

Chronic Kidney Disease

Chronic kidney disease (CKD) is a long-term condition in which the kidneys gradually lose their ability to filter waste products and excess fluid from the blood, leading to a sustained decline in kidney function. It is typically identified through reduced estimated glomerular filtration rate, abnormal blood and urin…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 80× across the literature 🔖 ISSN 2574-4488 🗓 Reviewed July 2026

Overview

Chronic kidney disease (CKD) is a long-term condition in which the kidneys gradually lose their ability to filter waste products and excess fluid from the blood, leading to a sustained decline in kidney function. It is typically identified through reduced estimated glomerular filtration rate, abnormal blood and urine markers such as elevated blood urea nitrogen, or imaging, and it is staged according to severity. Because the kidneys regulate fluid balance, blood pressure, red-blood-cell production, and mineral and bone metabolism, CKD can cause hypertension, anaemia, bone disease, and an increased risk of cardiovascular complications and heart failure. The disease frequently coexists with diabetes and hypertension and may progress to end-stage kidney disease requiring dialysis or transplantation. Research in this area examines the underlying mechanisms of kidney injury and renal fibrosis, associated endocrine and haematological disturbances, and the management of complications. The journal publishes peer-reviewed studies relevant to these themes, including thyroid function abnormalities in CKD, dipper versus non-dipper blood-pressure patterns by disease stage, distinguishing depression from apathy in affected patients, contrast-agent nephrotoxicity, glomerular filtration changes, the role of BCL-2 and BAK genes in haemodialysis patients, mechanisms and therapeutic targets of renal fibrosis, and hepcidin-related anaemia of chronic kidney disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 80 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Chronic Kidney Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Nephrology Advances (ISSN 2574-4488).

Journal editorial board
Ying-Yong Zhao · United States Santiago Cuevas · United States Istvan Arany · United States

This page summarises published research for orientation; it is not medical or professional advice.