Radiation therapy is the use of high-energy ionising radiation, such as X-rays, gamma rays, or charged particles, to destroy cancer cells or shrink tumours by damaging their DNA. It is delivered through external-beam techniques and internal approaches such as brachytherapy, and it may be used alone or combined with …
Radiation therapy is the use of high-energy ionising radiation, such as X-rays, gamma rays, or charged particles, to destroy cancer cells or shrink tumours by damaging their DNA. It is delivered through external-beam techniques and internal approaches such as brachytherapy, and it may be used alone or combined with surgery, chemotherapy, or immunotherapy. Precise treatment planning is essential, including the definition of target volumes for radiosurgery of tumours such as atypical meningiomas, and comparisons of two- and three-dimensional brachytherapy in cervical cancer assess how delivery technique affects outcome. Combining radiation with immunotherapy is an active strategy, illustrated by its use in melanoma, where the two modalities may act synergistically. The field also addresses radiation-related toxicity and safety, including adverse events after treatment, radiation-induced second malignancies such as maxillary angiosarcoma, and household radiation exposure following radioiodine ablation. Its application spans diverse cancers, from prostate and cervical to head-and-neck and paediatric nasopharyngeal carcinoma. Research in this area develops and refines radiation techniques and treatment planning, evaluates combinations with systemic therapies, examines treatment-related toxicity and safety, and assesses outcomes across the many cancer types for which radiation therapy is a central component of care.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 83 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Radiation Therapy, linking to each citing work.