Research Topic · Peer-Reviewed

Sclerosis

Sclerosis denotes the abnormal hardening of tissue through scarring, fibrosis, or gliosis, and in neurology the term is most closely associated with multiple sclerosis, a chronic immune-mediated disease of the central nervous system in which inflammatory demyelination and axonal loss produce disseminated lesions in …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 15× across the literature 🗓 Reviewed July 2026

Overview

Sclerosis denotes the abnormal hardening of tissue through scarring, fibrosis, or gliosis, and in neurology the term is most closely associated with multiple sclerosis, a chronic immune-mediated disease of the central nervous system in which inflammatory demyelination and axonal loss produce disseminated lesions in the brain, optic nerves, and spinal cord. Clinically, multiple sclerosis follows relapsing-remitting and progressive courses, presenting with optic and cranial nerve involvement, sensory and motor deficits, and accumulating disability quantified by validated severity measures. Research in this domain addresses pediatric-onset disease, neurovascular reactivity following relapses, and the prognostic factors governing disability progression in defined cohorts. Therapeutic and rehabilitative investigation spans phototherapy interventions such as ultraviolet B, evidence-based occupational therapy for rehabilitation, and coping strategies among affected individuals during periods of heightened vulnerability such as the COVID-19 pandemic, including questions of vaccine safety in this population. Related neuroinflammatory entities, including post-infectious acute disseminated encephalomyelitis, fall within the broader differential. Methodological work on blinding in neurological clinical research further informs trial design. The journal publishes peer-reviewed clinical cohort studies, case reports, rehabilitation research, and therapeutic trials addressing multiple sclerosis and related demyelinating disorders, their disability outcomes, and management strategies.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2015

Why Music in Neurology?

Raglio AlfredoCorresponding author
Department of Biomedical and Specialistic Surgical Sciences, Section of Neurological Clinic, University of Ferrara, Via Aldo Moro 8, 44100 Cona, Ferrara, Italy.
Exact topic Neurological Research and Therapy doi:10.14302/issn.2470-5020.jnrt-14-483
2014

Understanding Ubl-Rpn1 Intermolecular Interaction

Pradhan N.Corresponding author
Sr. Professor and Head, Department of Psychopharmacology, NIMHANS, Bangalore, INDIA, 560001
Exact topic Advanced Pharmaceutical Science And Technology Cited by 7 doi:10.14302/issn.2328-0182.japst-13-288

How this research is being cited

The 12 articles above have been cited 15 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Sclerosis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Multiple Sclerosis and Related Disorders.

Journal editorial board
Jorge Matias-Guiu · Spain Anne Vejux · France

This page summarises published research for orientation; it is not medical or professional advice.