Research Topic · Peer-Reviewed

Myelin

Myelin is the lipid-rich, multilayered membrane that wraps around the axons of many neurons, forming an insulating sheath that is essential for the rapid and efficient transmission of electrical impulses in the nervous system. In the central nervous system myelin is produced by oligodendrocytes, whose development is…

Curated from this journal's research 📚 8 peer-reviewed articles cited Cited 42× across the literature 🗓 Reviewed July 2026

Overview

Myelin is the lipid-rich, multilayered membrane that wraps around the axons of many neurons, forming an insulating sheath that is essential for the rapid and efficient transmission of electrical impulses in the nervous system. In the central nervous system myelin is produced by oligodendrocytes, whose development is governed by signalling pathways including Wnt, while in the peripheral nervous system it is formed by Schwann cells. Constituting the white matter of the brain and spinal cord, the myelin sheath is interrupted at regular intervals by nodes of Ranvier, enabling saltatory conduction in which the nerve impulse jumps between nodes, greatly increasing conduction velocity while conserving energy and space. Myelin also provides metabolic and trophic support to the axons it ensheathes. Damage to myelin, through demyelination or failure of its formation, slows or blocks conduction and produces neurological dysfunction. This underlies disorders such as multiple sclerosis, in which immune-mediated demyelination affects both adult and paediatric patients and is investigated through diagnostic and therapeutic studies including phototherapy trials, as well as leukodystrophies and leukoencephalopathies such as Canavan disease, where metabolic disturbance impairs myelin and astrocyte function. Understanding the biology of myelination, the cells that produce it, and the mechanisms of its injury and potential repair is central to neuroscience and to the development of treatments for demyelinating and dysmyelinating diseases.

Research published in this journal

8 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2020

The Novel Coronavirus 2019 (COVID-19): A Narrative Review

Rezapour BarataliCorresponding author
Department of Public Health, Faculty of Health, Assistant Professor, PhD in Health education and promotion, Urmia University of Medical Sciences, Urmia, Iran
Exact topic International Journal of Coronaviruses Cited by 2 doi:10.14302/issn.2692-1537.ijcv-20-3373

How this research is being cited

The 8 articles above have been cited 42 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Myelin, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Multiple Sclerosis and Related Disorders.

Journal editorial board
Jorge Matias-Guiu · Spain Anne Vejux · France

This page summarises published research for orientation; it is not medical or professional advice.