Evidence-based Medicine

Overview

Evidence-based medicine is the conscientious, explicit, and judicious use of the best available scientific evidence, integrated with clinical expertise and patient values, to guide decisions about the care of individual patients. It emerged as a framework for grounding practice in systematically appraised research rather than tradition, intuition, or unexamined authority. The approach involves formulating focused clinical questions, searching for relevant studies, critically appraising their validity and applicability, and applying the findings while accounting for the circumstances and preferences of the patient. Central to it is a hierarchy of evidence, in which well-designed randomized controlled trials and systematic reviews generally provide stronger support for causal and therapeutic claims than observational studies or expert opinion, underscoring why new drugs, treatments, and devices must be tested rigorously through clinical trials before adoption. Evidence-based medicine relies on critical appraisal to weigh study quality, bias, and the strength of conclusions, and it requires that established concepts be re-assessed as new evidence accumulates, as illustrated by the reconsideration of clinical and epidemiological assumptions during the COVID-19 pandemic. By emphasizing transparent, reproducible reasoning and the integration of research with clinical judgment, evidence-based medicine aims to improve the quality, consistency, and safety of care, reduce unwarranted variation, and support shared, informed decision-making between clinicians and patients across the breadth of medical practice.

Research published in this journal

8 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 8 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• Studies on 2-((2, 4-dihydroxybenzylidene) amino)-3-phenylpropanoic acid include antimicrobial, antidiabetic, antioxidant, anticancer, hemolysis, and theoretical QSAR
  2025 · Journal of Biomolecular Structure and Dynamics
• Studies on 2-((2, 4-dihydroxybenzylidene) amino)-3-phenylpropanoic acid include antimicrobial, antidiabetic, antioxidant, anticancer, hemolysis, and theoretical QSAR
  2023 · Journal of Biomolecular Structure and Dynamics
• Estrategias de intervención y posvención del comportamiento suicida
  2022 ·
• The opioid excess theory in autism spectrum disorders - is it worth investigating further?
  Katarzyna Tarnowska et al. · 2021 · Critical reviews in food science and nutrition
• A Review of the Efficacy of the Dietary Intervention in Autism Spectrum Disorder
  Z. Taha et al. · 2021 ·
• A Review of the Efficacy of the Dietary Intervention in Autism Spectrum Disorder
  2021 · Open Access Macedonian Journal of Medical Sciences
• The opioid excess theory in autism spectrum disorders - is it worth investigating further?
  2021 · Critical Reviews in Food Science and Nutrition
• Sero prevalence of SARS-CoV-2 in general population of Nagpur district
  2021 · International Journal of Community Medicine and Public Health

A sample of recent works citing this journal's research on Evidence-based Medicine, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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