Post-COVID-19 syndrome, also termed long COVID or post-acute sequelae of SARS-CoV-2 infection, refers to a constellation of symptoms and signs that persist or emerge beyond the acute phase of infection and cannot be explained by an alternative diagnosis. It is recognised across a substantial proportion of people who…
Post-COVID-19 syndrome, also termed long COVID or post-acute sequelae of SARS-CoV-2 infection, refers to a constellation of symptoms and signs that persist or emerge beyond the acute phase of infection and cannot be explained by an alternative diagnosis. It is recognised across a substantial proportion of people who have had COVID-19, including those with initially mild illness, and is characterised by symptoms lasting weeks to months, commonly fatigue, dyspnoea, chest pain, cognitive impairment, and disturbances of mood and sleep, reflecting potential multi-system involvement. Proposed mechanisms include persistent inflammation and immune dysregulation, endothelial and microvascular injury, organ damage sustained during acute disease, and autonomic dysfunction, with cytokine-mediated processes and the consequences of severe infection contributing to ongoing morbidity. Characterisation of the syndrome draws on the clinical course of acute infection, inflammatory and immunological profiling, and the recognition of complications following infection and vaccination. Recurring research themes include cytokine profiling in patients, immune and inflammatory responses to the virus and spike protein, the consequences of infection, and prognostic markers of severe disease. Research published in this area examines the persistent and post-acute manifestations of coronavirus infection and their underlying mechanisms, reflecting the journal's coverage of the longer-term consequences of COVID-19.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 13 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Post-Covid-19 Syndrome, linking to each citing work.