Overview
The lungs are the paired organs of gas exchange in the respiratory system, where inhaled air reaches the alveoli and oxygen and carbon dioxide diffuse across the thin alveolar-capillary membrane. Their architecture, from conducting airways to the vast alveolar surface served by the pulmonary microvasculature, makes them both highly efficient at respiration and a principal target of respiratory pathogens. In COVID-19, SARS-CoV-2 infects alveolar epithelial cells and drives a spectrum of pulmonary injury, including diffuse alveolar damage, acute pneumonia, and acute respiratory distress, accompanied by inflammatory cell recruitment, impaired gas exchange, and, in severe disease, microvascular thrombosis and fibrin deposition within pulmonary microthrombi. Imaging, particularly chest computed tomography, is central to characterising the extent and pattern of lung involvement, while proposed two-phase models describe the progression from early viral injury to later immune-mediated damage. Understanding these mechanisms informs oxygenation strategies, anti-inflammatory and antithrombotic therapy, and prognostication. The peer-reviewed research published in this area of the International Journal of Coronaviruses examines SARS-CoV-2 pulmonary pathogenesis, COVID-19 pneumonia and its differential features, lung damage mechanisms and leukocyte recruitment, fibrin-network changes in pulmonary microthrombi, and the role of chest computed tomography in characterising disease, alongside related respiratory and pulmonary studies in affiliated journals.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Novel Coronavirus 2019 (COVID-19): A Narrative Review
COVID-19-Induced Changes in the Fibrin Network of Pulmonary and Renal Microthrombi
The Impact of Chest Computed Tomography in A Covid-19 Reference Hospital - First Wave - Distrito Federal - Brazil
Two-Phase Lung Damage Mechanisms For COVID-19 Disease, and Driving Force and Selectivity in Leukecyte Recruitment and Migration
Impact of Biofield Energy Treatment Based Test Formulation on Vital Organ Health Specific Biomarkers Using Cell Line Study
Cell-Based Vital Organs Specific Biomarkers Assessment using Biofield Energy Based Novel Test Formulation
Acute Pneumonia and COVID-19: Problems of Today
COVID-19 and New Forms of Acute Pneumonia. It's Time for A Brainstorming Session
As Evidenced by the Statistics of the Pandemic
COVID-19 Pandemic: The Causative Agent is New, The Problem is Old
A Study on Contagious Bovine Pleuropneumonia in Khartoum State, Sudan
How this research is being cited
The 12 articles above have been cited 14 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · Natural Product Research
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2024 · Open Journal of Veterinary Medicine
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2024 · International Journal of Social health
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2024 · Open Journal of Veterinary Medicine
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Lufti Hajri et al. · 2024 · International Journal of Social Health
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2024 · Archives of Pulmonology and Respiratory Care
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2023 · Global Journal of Cancer Therapy
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2023 · Global Journal of Cancer Therapy
A sample of recent works citing this journal's research on Lungs, linking to each citing work.