Immunity is the capacity of an organism to resist or limit infection and disease through the combined action of innate and adaptive defence mechanisms. Innate immunity provides immediate, germline-encoded protection via barriers, phagocytic cells, complement, and type I and II interferons, while adaptive immunity ge…
Immunity is the capacity of an organism to resist or limit infection and disease through the combined action of innate and adaptive defence mechanisms. Innate immunity provides immediate, germline-encoded protection via barriers, phagocytic cells, complement, and type I and II interferons, while adaptive immunity generates antigen-specific T cell and antibody responses that mature over days and persist as immunological memory. Functionally, immunity is classified as active, acquired through natural infection or vaccination and characterised by durable memory, or passive, conferred temporarily by transfer of preformed antibodies such as convalescent plasma or therapeutic immunoglobulins. Against SARS-CoV-2, protective immunity depends on neutralizing antibodies directed at the spike glycoprotein, coordinated cytokine and interferon signalling, and T cell help; the concept of herd immunity, in which a sufficient proportion of immune individuals interrupts transmission, frames population-level control. Modulating these pathways through interferon therapy, nutraceuticals, passive antibody transfer, and vaccination is central to managing viral disease. The peer-reviewed research published in this area of the International Journal of Coronaviruses addresses antiviral immunity in COVID-19, including interferon-based immunomodulation, passive and artificial immunity strategies, neutralizing antibody and convalescent plasma approaches, herd immunity dynamics, and the influence of nutrition on host defence.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 24 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Immunity, linking to each citing work.