COVID-19 treatment encompasses the pharmacological and supportive interventions used to manage infection with SARS-CoV-2, the betacoronavirus that emerged in late 2019 and joined SARS-CoV and MERS-CoV as agents capable of causing severe respiratory disease. Management is stratified by disease severity and phase: sup…
COVID-19 treatment encompasses the pharmacological and supportive interventions used to manage infection with SARS-CoV-2, the betacoronavirus that emerged in late 2019 and joined SARS-CoV and MERS-CoV as agents capable of causing severe respiratory disease. Management is stratified by disease severity and phase: supportive and symptomatic care for mild illness, and for moderate-to-severe disease the addition of oxygen therapy, antiviral and immunomodulatory agents, anticoagulation, and organ support. Because severe disease reflects both viral replication and a dysregulated host inflammatory response, treatment strategy depends on timing, with antiviral approaches most relevant early and anti-inflammatory measures during the later hyperinflammatory phase. During the pandemic, repurposed drugs including hydroxychloroquine and chloroquine regimens were evaluated for clinical improvement, mortality, and viral kinetics, alongside interferon-based immunomodulation and cell therapy for the consequences of infection; laboratory markers such as white-cell and lymphocyte dynamics were studied to monitor response. Complications including secondary infections and vaccine-associated reactions also inform clinical decisions. Research published in this area examines therapeutic candidates, their mechanisms and measured outcomes, and the clinical course of infection, reflecting the journal's focus on the treatment of coronavirus disease.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 42 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Covid and Treatment, linking to each citing work.