Overview
A coronavirus vaccine is a biological preparation designed to induce protective immunity against a coronavirus, training the immune system to recognise viral antigens, most commonly the spike protein, so that subsequent infection is prevented or attenuated. Vaccine platforms include nucleic-acid, viral-vector, protein-subunit and inactivated approaches, each presenting antigen to elicit neutralising antibodies and cellular responses. In the context of SARS-CoV-2, vaccine development has confronted the dual challenge of rapid deployment and durable, broad protection, and research addresses the insights, prospects and challenges of bringing candidates from concept to use. Relevant work spans the immunological basis of protection, including neutralising antibodies and interferon and cytokine responses to the spike protein, and the safety considerations that accompany vaccination, such as rare post-vaccination reactions affecting the liver. The continual molecular evolution of the virus, documented through spike-gene sequence analysis and lineage comparison, bears directly on how well existing vaccines match circulating strains and motivates updated formulations. Vaccination interacts with other strategies, including immune modulation and measures to reduce infection risk. Understanding coronavirus vaccines therefore requires integrating immunology, virology and clinical evaluation to assess efficacy, safety and the need to adapt as the virus changes.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
A Data Mining Methodology for Detecting Conspiracy Theories from Scientific Articles: The Covid-19 Case
The Novel Coronavirus 2019 (COVID-19): A Narrative Review
COVID-19 Vaccine Development: Insights, Prospects and Challenges
Use of Immune Modulator Interferon-Gamma to Support Combating COVID-19 Pandemic
Cell Therapy as an Alternative approach for COVID-19 Infection Consequences: A Non-Systematic Review
Animals in the COVID-19 Era: Between Being a source, Victims, or Maybe our Hope to Overcome it!
Pyrexia And Liver Injury After A Second SARS-CoV-2 Vaccination: Macrophage Activation Manifested In Liver
Molecular Evolution of the Novel Coronavirus SARS-CoV-2
Reducing COVID-19 Risk through Dietary Supplementation of Plant Mannose Binding Lectins
Molecular Evolutionary Characteristics of the 2019 Novel Coronavirus (SARS-CoV-2) Contracted by Tunisian Citizens : Comparison and Relationship to Other Human and Animal Coronaviruses Based on Spike Glycoprotein-Coding Gene Sequences Analysis
SARS-CoV-2 affected cells Pathogeny and Therapy
How this research is being cited
The 12 articles above have been cited 24 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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R. Paulino-Ramírez et al. · 2023 · International Journal of Environmental Research and Public Health
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2023 · Revista Brasileira de Farmacognosia
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2023 · Revista Brasileira de Farmacognosia
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2023 · International Journal of Environmental Research and Public Health
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2023 · Frontiers in Medicine
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2023 · Frontiers in Medicine
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2022 · Biomedicine & Pharmacotherapy
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Cell Therapy as an Alternative approach for COVID-19 Infection Consequences: A Non-Systematic Review2021 · International Journal of Coronaviruses
A sample of recent works citing this journal's research on Coronavirus Vaccine, linking to each citing work.