Acute respiratory distress syndrome (ARDS) is a severe form of inflammatory lung injury characterized by diffuse damage to the alveolar–capillary barrier, leading to fluid accumulation, impaired gas exchange, and profound hypoxemia that often requires mechanical ventilation. It can be triggered by pneumonia, sepsis,…
Acute respiratory distress syndrome (ARDS) is a severe form of inflammatory lung injury characterized by diffuse damage to the alveolar–capillary barrier, leading to fluid accumulation, impaired gas exchange, and profound hypoxemia that often requires mechanical ventilation. It can be triggered by pneumonia, sepsis, trauma, or inhalation injury. During the COVID-19 pandemic, severe SARS-CoV-2 infection became a prominent cause of ARDS, as the virus and the host inflammatory response combined to injure lung tissue. The articles assembled here address this intersection of viral infection and severe lung injury. Several examine the immune and inflammatory dimensions of COVID-19, including cytokine profiling in hospitalized patients and the role of spike protein in modulating interferon and cytokine gene expression. Therapeutic and management questions appear in work on cell-based therapy for COVID-19 sequelae, evaluation of hydroxychloroquine on clinical improvement and mortality, and scoring systems for predicting mortality risk in COVID-19 pneumonia. Diagnostic imaging is represented by analysis of chest computed tomography in a reference hospital, while broader contributions consider transmission, prevention, herd immunity, and the mental-health burden of the pandemic. Together these studies illustrate how ARDS in the COVID-19 context is investigated through its inflammatory mechanisms, clinical course, imaging features, and treatment strategies, all aimed at reducing mortality from this critical condition.
11 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 11 articles above have been cited 16 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Acute Respiratory Distress Syndrome and Covid, linking to each citing work.