Overview
Acute kidney injury (AKI) is an abrupt, potentially reversible decline in renal function occurring over hours to days, defined by a rise in serum creatinine, a fall in urine output, or both, with consequent retention of nitrogenous waste and disturbances of fluid, electrolyte, and acid-base balance. It is conventionally classified by mechanism into prerenal azotaemia (renal hypoperfusion from hypovolaemia, sepsis, or cardiac failure), intrinsic renal injury (most often acute tubular necrosis, but also interstitial nephritis and glomerular disease), and postrenal obstruction. Staging systems such as RIFLE, AKIN, and KDIGO grade severity by creatinine increment and oliguria. In the setting of severe viral respiratory illness, AKI may arise through haemodynamic instability, cytokine-mediated injury, direct tubular involvement, and microvascular thrombosis; nephrotoxic exposures including iodinated contrast media and certain drugs compound the risk. Cardiorenal interactions, delayed graft function after transplantation, and chronic kidney disease as a predisposing substrate are recurring clinical themes. The condition is associated with increased morbidity, prolonged hospitalisation, and progression to chronic kidney disease. Research published in this area examines pathophysiology, biomarkers, contrast nephropathy, transplant haemodynamics, and renal outcomes in critically ill and infected patients.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Toxicity of Iodinated Radiographic Contrast Agents in the Clinical Practice
Cardiorenal Signaling Pathways in Heart Failure: Good and Bad News
Living Kidney Transplant: The Influence of Intra-Operative Hemodynamics on Delayed Graft Function
Comparison of Dipper and Non-Dipper Hypertension Patterns According to Chronic Kidney Disease Stage
Mucormycosis: A Surge in Mucorales Fungal Infection in Post – Covid Patients in Indian States and Insight into Known and Unknown Factors
Cell Therapy as an Alternative approach for COVID-19 Infection Consequences: A Non-Systematic Review
Outcomes in Sequential Intragastric Balloon Treatment for Patients With Super Obesity - A Single Centre Retrospective Analysis
Proteomic and Genomic Techniques in Medical Research: Applications in Cancer, Diagnostics, and Personalized Medicine
Renal Function in Patients with Acute Myocardial Infarction: A Current Perspective.
Redefining Coronavirus: Update on the Impacts of COVID-19 in the Rural Areas of Abia State
Haematuria in the Elderly: a Review
How this research is being cited
The 12 articles above have been cited 56 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
-
2026 · Cereal Research Communications
-
2026 · South African Journal of Botany
-
Rupam Saha et al. · 2025 · Medicine in Novel Technology and Devices
-
Ibrahim Halil Kenger et al. · 2025 · Journal of Applied Toxicology
-
Yuping Zhang et al. · 2025 · Biomaterials
-
2025 · Journal of Applied Toxicology
-
2025 · Biomaterials
-
2025 · Medicine in Novel Technology and Devices
A sample of recent works citing this journal's research on Acute Kidney Injury, linking to each citing work.