In vivo animal models are living organisms used in research to study biological processes, disease mechanisms, and therapeutic interventions under physiologically relevant conditions that cannot be fully replicated in cell culture or computational systems. Research published in In-vitro In-vivo In-silico Journal add…
In vivo animal models are living organisms used in research to study biological processes, disease mechanisms, and therapeutic interventions under physiologically relevant conditions that cannot be fully replicated in cell culture or computational systems. Research published in In-vitro In-vivo In-silico Journal addresses the integration of in vivo animal models within comprehensive drug development pipelines that combine computational predictions, laboratory testing, and whole-organism validation. Published work has examined the progression from computational drug design through in vitro screening to in vivo confirmation, demonstrating how animal models serve as critical validation tools for candidate compounds identified through earlier-stage methods. Specific studies have investigated structure-activity relationships of natural product derivatives, including xanthones from mangosteen, where in vivo models help confirm inhibitory activity against molecular targets such as cyclin-dependent kinases that were initially identified through computational and cell-based approaches. This topic matters because in vivo animal models remain essential for understanding systemic pharmacokinetics, toxicity, and efficacy before human trials, bridging the gap between isolated molecular observations and clinical translation. The journal's coverage emphasizes the complementary roles of computational, in vitro, and in vivo methods in modern biomedical research.
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 2 articles above have been cited 53 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on in Vivo Animal Models, linking to each citing work.