Cancer immunotherapy is a treatment approach that harnesses the immune system to recognise and destroy malignant cells. Rather than acting directly on the tumour as chemotherapy or radiation do, immunotherapy stimulates, restores, or engineers immune responses so that the body's own defences can target cancer while …
Cancer immunotherapy is a treatment approach that harnesses the immune system to recognise and destroy malignant cells. Rather than acting directly on the tumour as chemotherapy or radiation do, immunotherapy stimulates, restores, or engineers immune responses so that the body's own defences can target cancer while ideally sparing healthy tissue. It builds on the understanding that tumours can evade immune surveillance, and it seeks to overcome that evasion through diverse strategies. These include checkpoint inhibitors that release natural brakes on immune cells, adoptive cell therapies such as engineered CAR-T cells, cancer vaccines, and approaches that exploit tumour-associated antigens. Advances in immunomonitoring, including modern immunoassays and immunogenomic methods, support the assessment of immune responses in cancer and infectious disease and help guide and evaluate treatment. Research illustrating the field spans the conceptual framing of immunotherapy as a novel therapeutic avenue, the study of oncofoetal antigens such as alpha-fetoprotein and its receptor, the integration of nanotechnology with cell-based therapies, and the application of immunotherapy across tumour types including lung cancer and melanoma. Key themes are the mechanisms of immune recognition and tumour escape, the development of agents that potentiate antitumour immunity, and the use of biomarkers to predict and monitor response. By mobilising immune defences against malignancy, cancer immunotherapy has expanded treatment options and reshaped the management of many cancers.
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 7 articles above have been cited 6 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Cancer Immunotherapy, linking to each citing work.