Obesity is a chronic, relapsing disease characterised by the excessive accumulation of body fat that impairs health, most commonly classified using body mass index together with central and anthropometric measures such as waist circumference, waist-to-hip ratio and waist-to-height ratio that capture the distribution…
Obesity is a chronic, relapsing disease characterised by the excessive accumulation of body fat that impairs health, most commonly classified using body mass index together with central and anthropometric measures such as waist circumference, waist-to-hip ratio and waist-to-height ratio that capture the distribution of adiposity. It arises from a sustained positive energy balance shaped by interacting genetic, endocrine, behavioural, dietary and environmental determinants, and is sustained by the active physiology of adipose tissue, which functions as an endocrine organ secreting adipokines and inflammatory mediators that influence insulin sensitivity, vascular tone and lipid metabolism. Excess and particularly visceral adiposity is a principal modifiable risk factor for hypertension, type 2 diabetes, dyslipidemia, metabolic syndrome and cardiovascular disease. Studies in this area examine the prevention of overweight and obesity, behaviour modification strategies, the physiology and metabolic activity of adipose tissue, and the use of central-obesity anthropometric indicators alongside measures of body composition and skeletal muscle mass to characterise risk and treatment response. Related experimental work investigates dietary and pharmacological approaches, including plant-derived compounds tested in animal models, that target adiposity and its downstream metabolic and vascular consequences.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 81 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Obesity, linking to each citing work.