Metabolic syndrome is a clustering of interrelated cardiometabolic risk factors, central (abdominal) obesity, elevated blood pressure, raised fasting glucose or insulin resistance, elevated triglycerides, and reduced high-density-lipoprotein cholesterol, that together substantially increase the risk of type 2 diabet…
Metabolic syndrome is a clustering of interrelated cardiometabolic risk factors, central (abdominal) obesity, elevated blood pressure, raised fasting glucose or insulin resistance, elevated triglycerides, and reduced high-density-lipoprotein cholesterol, that together substantially increase the risk of type 2 diabetes and atherosclerotic cardiovascular disease. Insulin resistance and visceral adiposity are widely regarded as core drivers, linking dysfunctional adipose tissue, chronic low-grade inflammation, dyslipidaemia, and endothelial dysfunction, with hypertension a defining and mechanistically integrated component. Within Hypertension and Cardiology, metabolic syndrome is studied for its prevalence and determinants across populations and occupational groups, its anthropometric and biochemical markers of central obesity and metabolic risk, and its pathophysiological connections to adipose-tissue physiology, hyperlipidaemia, and glucose dysregulation. Research also addresses associations with psychiatric and pharmacological factors, including syndrome risk among patients treated with antipsychotic and antidepressant medication, and the evaluation of dietary and nutritional interventions, such as antioxidant micronutrients and specific functional foods, for modifying its components. These lines of inquiry connect metabolic syndrome to obesity, diabetes, and cardiovascular prevention. This topic compiles peer-reviewed research relevant to the definition, prevalence, anthropometric and metabolic markers, pathophysiology, and management of metabolic syndrome, reflecting its position at the intersection of metabolic and cardiovascular disease.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 24 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Metabolic Syndrome, linking to each citing work.