Overview
Coronary artery bypass grafting (CABG) is a surgical revascularisation procedure that restores blood supply to the myocardium by routing it around segments of coronary artery narrowed or occluded by atherosclerotic plaque. In coronary artery disease, plaque accumulation limits perfusion and can cause angina, breathlessness, ischaemia, and myocardial infarction. During CABG the surgeon harvests a conduit, commonly the internal mammary (thoracic) artery, radial artery, or saphenous vein, and anastomoses it so that oxygenated blood bypasses the diseased segment and reaches the ischaemic territory beyond it. The operation may be performed with cardiopulmonary bypass and cardioplegic arrest or as off-pump surgery on the beating heart, and blood-conservation strategies such as acute normovolemic hemodilution are used to reduce transfusion. CABG is generally favoured for left main disease, multivessel disease, and chronic total occlusions, and is weighed against percutaneous coronary intervention according to lesion complexity, comorbidity, and ventricular function. Anatomical variation in the left coronary artery and its branches influences both grafting and catheter-based approaches. Outcomes depend on graft patency, completeness of revascularisation, and perioperative management, with long-term care directed at secondary prevention, risk-factor control, and surveillance for graft failure and disease progression.
Research published in this journal
5 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Percutaneous Intervention for Quadrifurcation Lesion of the Left Main Coronary Artery
ANH in Complex Cardiac Surgery: A Prospective Randomized Study
Variations in Diameter of the Left Coronary Artery and its Main Branches among Adult Population of Khartoum State, Sudan
MicroRNA: New Era for Therapeutic Strategy in Ischaemic Heart Disease
How this research is being cited
The 5 articles above have been cited 17 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · Reviews in Cardiovascular Medicine
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2025 · Medical & Biological Engineering & Computing
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2025 · Reviews in Cardiovascular Medicine
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2025 · Medical & Biological Engineering & Computing
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2024 · Journal of Materials Chemistry B
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2024 · Journal of Materials Chemistry B
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2023 · Science Progress
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2023 · Cureus
A sample of recent works citing this journal's research on Coronary Artery Bypass Grafting, linking to each citing work.