Cardiomyocytes are the muscle cells that make up the myocardium, the contractile tissue of the heart, and are responsible for generating the rhythmic contractions that pump blood throughout the body. These specialized cells are rich in mitochondria to meet their high energy demands and are connected to one another i…
Cardiomyocytes are the muscle cells that make up the myocardium, the contractile tissue of the heart, and are responsible for generating the rhythmic contractions that pump blood throughout the body. These specialized cells are rich in mitochondria to meet their high energy demands and are connected to one another in a way that allows coordinated electrical and mechanical activity. Because adult cardiomyocytes have limited capacity to regenerate, injury or stress to the heart, such as that caused by hypertension, ischemia, or toxic agents, can lead to lasting damage and contribute to heart failure. Cardiomyocytes are therefore central to cardiovascular research, including studies of cardiac function, disease mechanisms, drug safety, and regenerative approaches. Research within Hypertension and Cardiology relevant to this topic includes a study assessing cardiac function using a rat cardiomyocyte cell line, an evaluation of calcium-transient assays in human induced pluripotent stem cell-derived cardiomyocytes for compound screening, and work on in vitro disease models used in preclinical cardiotoxicity and safety testing. These studies illustrate how cardiomyocyte models are used to investigate heart function and the cardiac effects of drugs. This page gathers peer-reviewed, open-access research relevant to cardiomyocytes, cardiac muscle biology, and cardiovascular disease and safety research.
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 7 articles above have been cited 57 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Cardiomyocytes, linking to each citing work.