Neoplasms are abnormal, autonomous proliferations of tissue resulting from acquired genetic and epigenetic alterations that uncouple cell growth from normal regulatory controls. They are classified as benign, when localized and non-invasive, or malignant, when capable of invading surrounding tissue and metastasizing…
Neoplasms are abnormal, autonomous proliferations of tissue resulting from acquired genetic and epigenetic alterations that uncouple cell growth from normal regulatory controls. They are classified as benign, when localized and non-invasive, or malignant, when capable of invading surrounding tissue and metastasizing, and are further categorized by tissue of origin into carcinomas, sarcomas, hematolymphoid neoplasms, and tumors of the central nervous system. Their pathogenesis involves driver mutations in oncogenes and tumor-suppressor genes, dysregulated signaling, genomic instability, epithelial-mesenchymal transition, and acquisition of cancer stem-cell properties, while diagnosis and staging integrate histopathology, immunohistochemistry, imaging, and increasingly molecular profiling. Within hematology and oncology, neoplasms span solid tumors and hematologic malignancies, and their study addresses epidemiology, classification, second malignancies, and the distinction between primary tumors and metastases. The journal publishes peer-reviewed research across this breadth, including epidemiological analyses of malignant brain and central nervous system neoplasms, plasmacytoma and monoclonal gammopathy, polycythemia vera, thyroid neoplasia, radiosurgical management of atypical meningiomas, non-Hodgkin lymphoma, and experimental characterization of solid human tumor cell behavior in vitro. This research reflects the diagnostic, prognostic, and therapeutic complexity of benign and malignant tumors and the integration of pathology, cytogenetics, and clinical oncology in their management.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 83 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Neoplasms, linking to each citing work.