Immune-mediated diseases are disorders in which an inappropriate or dysregulated immune response drives tissue injury and clinical illness. They include classic autoimmune conditions, in which adaptive immunity targets self-antigens; immune-mediated cytopenias, in which blood cells are destroyed; and chronic inflamm…
Immune-mediated diseases are disorders in which an inappropriate or dysregulated immune response drives tissue injury and clinical illness. They include classic autoimmune conditions, in which adaptive immunity targets self-antigens; immune-mediated cytopenias, in which blood cells are destroyed; and chronic inflammatory diseases in which sustained immune activation damages organs. Mechanisms range from autoantibody production and complement activation to T-cell-mediated cytotoxicity and disordered cytokine signalling, and the same patient may develop overlapping syndromes when tolerance fails across multiple tissues. The research collected here spans several of these presentations. Studies of autoimmunity include the rare co-occurrence of neuroimmunological conditions consistent with an autoimmune polyglandular syndrome, illustrating how immune dysregulation can affect several organs simultaneously. Haematological immune-mediated disease is represented by work on the laboratory diagnosis and treatment of immune thrombocytopenia, where platelets are immunologically destroyed, and by investigations of immune disturbance and suppression in the context of haematological disorders and chemotherapy. Inflammatory and mucosal immunity feature in experimental models of ulcerative colitis used to evaluate anti-inflammatory and antioxidant interventions. Together these contributions frame immune-mediated diseases as a broad and clinically important category unified by aberrant immune activity, and they reflect efforts to characterise their mechanisms, improve diagnostic testing, and identify therapeutic strategies that restore immune balance and limit tissue damage.
9 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 9 articles above have been cited 65 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Immune-mediated Diseases, linking to each citing work.