Overview
Circulating tumor DNA, often abbreviated ctDNA, consists of small fragments of DNA shed from tumor cells into the bloodstream. Because these fragments carry the genetic alterations of the cancer from which they originate, they can be detected and analyzed in a blood sample, forming the basis of a minimally invasive approach often called liquid biopsy. In hematology and oncology, ctDNA analysis is studied for its potential to detect cancer, characterize its mutations, monitor response to therapy, identify the emergence of treatment resistance, and detect minimal residual disease or recurrence, sometimes earlier than conventional imaging. Its appeal lies in avoiding the need for repeated tissue biopsies while capturing the genetic heterogeneity of a tumor over time, though sensitivity, standardization, and interpretation remain active areas of investigation. Research published through Hematology and Oncology Research engages with circulating biomarkers and immunogenomic approaches to cancer, including a study of dynamic microRNA expression in the plasma of melanoma patients in relation to disease progression and survival, and a review of current immunoassays and emerging immunogenomic methods for monitoring cancer and infectious diseases. This page gathers peer-reviewed, open-access scholarship relevant to circulating tumor DNA and blood-based approaches to cancer detection and monitoring.
Research published in this journal
8 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Current Immunoassays and Emerging Immunogenomic Approaches for Immunomonitoring Cancer and Infectious Diseases
RET 898-901Del mutant, a variant of unknown significance, has a durable response to Pralsetinib in a Medullary Thyroid Carcinoma patient
Role of Tie2, CD14, Angiopoietin as Angiogenetic Markers in Hepatocellular Carcinoma Complicating Hepatitis C Virus Infection
Targeting Cell Metabolism in Chronic Lymphocytic Leukaemia (CLL); Aviable Therapeutic Approach?
Lineage-Specific Disruption of Hematopoiesis by Oxaliplatin: Mechanisms of Erythropoietin Resistance and Immune Suppression
Understanding Inherited Bleeding Disorders: Genetic Mutations in Blood Coagulation Factors and Regulatory Proteins
An Update on Hemocytes in Biomphalaria Snails
How this research is being cited
The 8 articles above have been cited 45 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
-
2026 · Human Gene
-
2026 · Molecular Pain
-
Alya Mashaal et al. · 2025 · J. Comput. Aided Mol. Des.
-
Amina M. Ibrahim et al. · 2025 · Ecotoxicology
-
2025 · Journal of Computer-Aided Molecular Design
-
2025 · Ecotoxicology
-
El-Emam et al. · 2024 · Egyptian Journal of Aquatic Biology and Fisheries
-
S.E. Mohammed et al. · 2024 · Journal of Helminthology
A sample of recent works citing this journal's research on Circulating Tumor Dna, linking to each citing work.