Research Topic · Peer-Reviewed

Beta-thalassemia

Beta-thalassemia is an inherited blood disorder in which mutations in the HBB gene reduce or eliminate production of beta-globin, one of the protein chains that combine to form adult hemoglobin. Because hemoglobin is the molecule in red blood cells that carries oxygen throughout the body, insufficient beta-globin le…

Curated from this journal's research 📚 3 peer-reviewed articles cited Cited 18× across the literature 🔖 ISSN 2372-6601 🗓 Reviewed July 2026

Overview

Beta-thalassemia is an inherited blood disorder in which mutations in the HBB gene reduce or eliminate production of beta-globin, one of the protein chains that combine to form adult hemoglobin. Because hemoglobin is the molecule in red blood cells that carries oxygen throughout the body, insufficient beta-globin leads to imbalanced globin chains, ineffective red blood cell production, and varying degrees of anemia. The condition is classified along a spectrum according to severity, ranging from the mild, often symptomless beta-thalassemia minor seen in carriers to the severe, transfusion-dependent beta-thalassemia major, with intermediate forms in between. Management commonly involves regular blood transfusions, iron-chelation therapy to counter transfusion-related iron overload, and, in selected cases, curative approaches such as stem-cell transplantation. As an inherited hemoglobin disorder, beta-thalassemia sits within the broader hematology field covered by this journal. Research published in the journal has examined the everyday impact of thalassemia, including a study reporting reduced physical activity patterns in patients with thalassemia compared with healthy controls, highlighting the functional consequences of chronic anemia. This page gathers peer-reviewed, open-access research relevant to beta-thalassemia and related hematological conditions, supporting clinicians and researchers studying inherited blood disorders.

Research published in this journal

3 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 3 articles above have been cited 18 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Beta-thalassemia, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hematology and Oncology Research (ISSN 2372-6601).

Journal editorial board
Jayadev Manikkam Umakanthan · United States Shuaiying Cui · United States Benedetto Sacchetti · Italy

This page summarises published research for orientation; it is not medical or professional advice.