Overview
Female infertility is the inability of a woman to achieve or sustain pregnancy after a defined period of regular unprotected intercourse, attributable to factors within the female reproductive system. It is diagnosed alongside its male counterpart and may arise from disorders of ovulation, the fallopian tubes, the uterus, the cervix, or the peritoneal environment. Common mechanisms include hormonal dysregulation of the hypothalamic-pituitary-ovarian axis, diminished ovarian reserve and premature ovarian insufficiency, tubal obstruction or pelvic adhesions, endometriosis, and uterine structural anomalies. A clinically important subset is unexplained infertility, in which standard evaluation reveals no identifiable cause, prompting investigation of subtler immunological and biochemical contributors. Research in this area increasingly examines candidate biomarkers, such as immunoglobulin and complement profiles in the preconception period, as windows onto immune-mediated implantation failure. Regenerative approaches, including the study of mesenchymal stem cells for ovarian aging and primary ovarian insufficiency, explore restoration of follicular function. Diagnostic workup typically combines ovulation tracking, hormone assays, tubal patency testing, and imaging. Effective characterization of female infertility supports targeted interventions ranging from ovulation induction and surgical correction to assisted reproductive technologies, while biomarker discovery aims to refine prognosis and individualize treatment for couples facing reproductive difficulty.
Research published in this journal
5 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Therapeutic Potential of Autologous Adipose Derived Mesenchymal Stem Cells in Human POI and Ovarian Aging
Morphological Features of Testicular Biopsies in Infertile Males at a Tertiary Hospital, Southwest Nigeria
Daily Saliva and Vaginal Mucins Co-vary in Protein-to-Carbohydrate Ratio
How this research is being cited
The 5 articles above have been cited 10 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
-
2026 · Journal of Clinical Pathology
-
Hadeel Salih Mahmoud et al. · 2024 · Samarra Journal of Pure and Applied Science
-
Zahirrah Begam Mohamed Rasheed et al. · 2023 · Biology
-
2023 · Biology
-
2023 ·
-
2023 ·
-
Luján Irastorza Jesús Estuardo et al. · 2022 · Obstetrics & Gynecology International Journal
-
2022 · Obstetrics & Gynecology International Journal
A sample of recent works citing this journal's research on Female Infertility, linking to each citing work.