Research Topic · Peer-Reviewed

Toxicity

Toxicity is the capacity of a substance to cause harm to living organisms, characterized by the relationship between dose, exposure duration, and adverse biological effect. Toxicology distinguishes acute, subacute, subchronic, and chronic toxicity, and evaluates outcomes ranging from organ-specific injury and oxidat…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 95× across the literature 🔖 ISSN 2641-7669 🗓 Reviewed July 2026

Overview

Toxicity is the capacity of a substance to cause harm to living organisms, characterized by the relationship between dose, exposure duration, and adverse biological effect. Toxicology distinguishes acute, subacute, subchronic, and chronic toxicity, and evaluates outcomes ranging from organ-specific injury and oxidative stress to genotoxicity, neurotoxicity, and lethality. Mechanistic understanding centers on absorption, distribution, metabolism, and excretion, the generation of reactive intermediates, and the disruption of cellular homeostasis, while risk characterization relies on dose-response analysis and derivation of exposure limits such as minimal risk levels. The peer-reviewed research collected here reflects these themes through studies of carbon-tetrachloride-induced hepatic oxidative stress and protective agents, acute and subacute toxicity of plant extracts in rodents, and ecotoxicological assessment of landfill leachate. Aquatic toxicology features prominently, with work on paraquat, herbicide, hexavalent chromium, and cypermethrin effects in fish, including hematological and metabolomic endpoints. Additional contributions address microcystin attenuation, nickel toxicity in plants, cadmium exposure risk derivation, and computational systems-biology approaches to toxicity prediction. Methodologically, the literature spans rodent and fish bioassays, histopathology, clinical case reporting, and in silico modeling, illustrating how toxicity assessment integrates experimental and clinical evidence to evaluate chemical hazard, support regulation, and protect environmental and human health.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 95 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Toxicity, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Experimental and Clinical Toxicology (ISSN 2641-7669).

Journal editorial board
Roy Gerona · United States Bulent Uysal · United States Ichiro Kawahata · Japan

This page summarises published research for orientation; it is not medical or professional advice.