A cytotoxicity assay is a laboratory test used to measure the degree to which a chemical, drug, nanomaterial, or biological agent damages or kills living cells. Such assays are fundamental tools in toxicology and pharmacology, used to screen candidate drugs, evaluate the safety of chemicals and environmental contami…
A cytotoxicity assay is a laboratory test used to measure the degree to which a chemical, drug, nanomaterial, or biological agent damages or kills living cells. Such assays are fundamental tools in toxicology and pharmacology, used to screen candidate drugs, evaluate the safety of chemicals and environmental contaminants, and quantify the anticancer potential of compounds against cultured cell lines. They typically assess endpoints such as cell viability, membrane integrity, metabolic activity, or the induction of programmed cell death, and they provide quantitative measures of potency and toxicity that guide further development and risk assessment. Research relevant to cytotoxicity testing in the OpenAccessPub portfolio includes an in vitro study assessing the anticancer effect of alendronate in breast cancer cells, which evaluates the agent's cell-killing activity, and a study examining the cytotoxic and apoptotic activity of silver nanoparticles on HT-29 and A549 cell lines, which applies cytotoxicity assessment to nanomaterials. These studies illustrate how cytotoxicity assays are used to characterize the cellular effects of both pharmacological and nanomaterial agents. This page gathers peer-reviewed, open-access research relevant to cytotoxicity assays and their role in evaluating the safety and biological activity of substances.
4 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 4 articles above have been cited 42 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Cytotoxicity Assay, linking to each citing work.